The Use of Hexacapron in Upper Gastrointestinal Bleeding

2014/2/18 12:00

Conditions: Upper Gastrointestinal Bleeding; Hexacapron; Hemostasis; Rebleeding; Mortality
Interventions: Drug: Hexacapron( Tranexamic acid); Drug: esomeprazole
Sponsor: Shaare Zedek Medical Center
Not yet recruiting - verified February 2014

Clinical Trials on Evaluate the Red Ginseng and Fermented-Red Ginseng Affect to Drug Metabolizing Enzyme and Transporter in Healthy Volunteers

2014/2/2 12:00

Condition: Healthy
Interventions: Drug: CYP cocktail; Drug: Fexofenadine 30mg; Dietary Supplement: Red ginseng; Dietary Supplement: Fermented-red ginseng
Sponsor: Chonbuk National University Hospital
Completed - verified October 2013

Multicentric Randomized Study of H. Pylori Eradication and Pepsinogen Testing for Prevention of Gastric Cancer Mortality

2014/1/27 12:00

Conditions: Helicobacter Pylori Infections; Atrophic Gastritis; Gastric Cancer
Intervention: Drug: Triple therapy
Sponsors: International Agency for Research on Cancer; University of Latvia, Latvia; Vitebsk Medical University, Belarus; Research Institute of Internal Medicine, Novosibirsk, Russia; Research institute for Nordic Nations, Krasnoyarsk, Russia; Technion, Israel Institute of Technology; Karolinska Institutet; 4Pharma Ltd.; Academic Histology laboratory, SIA, Latvia
Recruiting - verified January 2014

Study to Determine the Potential DDIs When the Daclatasvir/Asunaprevir/BMS-791325 Three Drug Antiviral Combination Tablet (FDC) is Coadministered With a Cocktail of Cytochrome P450 (CYP) Probe Substrates and Transporter Probe Substrates (Digoxin and Pravastatin) in Healthy Subjects

2014/1/23 12:00

Condition: Hepatitis C
Interventions: Drug: Cocktail; Drug: DCV 3DAA FDC; Drug: BMS-791325
Sponsor: Bristol-Myers Squibb
Not yet recruiting - verified January 2014

Phase 3 Study to Evaluate the Acid-Inhibitory Effect of Multiple Oral Doses of TAK-438

2014/1/14 12:00

Condition: Healthy
Interventions: Drug: TAK-438, esomeprazole; Drug: Esomeprazole, TAK-438; Drug: TAK-438, rabeprazole sodium; Drug: Rabeprazole sodium, TAK-438
Sponsor: Takeda
Not yet recruiting - verified January 2014

Study to Evaluate the Safety and Efficacy of CJ-12420 in Patients With Erosive Esophagitis

2014/1/5 12:00

Conditions: Erosive Esophagitis; GERD
Interventions: Drug: CJ-12420; Drug: Esomeprazole
Sponsor: CJ Cheiljedang Corporation
Recruiting - verified January 2014

"Pharmacodynamic Comparison of Omeprazole Versus Pantoprazole on Platelet Reactivity in Patients With Acute Coronary Syndromes on Dual Antiplatelet Therapy With New P2Y12 Inhibitors" -Trial dOPPLER-

2014/1/2 12:00

Condition: Coronary Artery Disease
Interventions: Drug: Pantoprazole,; Drug: Omeprazole
Sponsor: University of Roma La Sapienza
Not yet recruiting - verified January 2014

A Study Investigating the Effect of Food and Esomeprazole on the Single Oral Dose Pharmacokinetics of RO5424802 in Healthy Volunteers.

2013/12/23 12:00

Condition: Healthy Volunteer
Interventions: Drug: RO5424802; Other: Hight fat and calorie meal; Other: Standard meal; Drug: esomeprazole
Sponsor: Hoffmann-La Roche
Not yet recruiting - verified December 2013

Effect of PPIs on Pediatric Microbiome

2013/12/16 12:00

Condition: Clostridium Difficile Infection
Interventions: Drug: Omeprazole (suspension); Other: Lifestyle Modification
Sponsor: Columbia University
Not yet recruiting - verified December 2013

A Phase II Trial of Proton Pump Inhibitors With Chemotherapy in Patients With Metastatic Head and Neck Cancer

2013/12/11 12:00

Condition: Cancer of Head and Neck
Interventions: Drug: Omeprazole; Drug: Carboplatin; Drug: 5FU; Drug: Paclitaxel; Drug: Pemetrexed
Sponsor: University of Michigan Cancer Center
Not yet recruiting - verified December 2013

Placebo In Chronic Pain

2013/12/9 12:00

Condition: Chronic Back Pain
Interventions: Drug: Naproxen; Drug: Placebo; Drug: Omeprazole
Sponsors: Northwestern University; National Center for Complementary and Alternative Medicine (NCCAM); National Institutes of Health (NIH)
Not yet recruiting - verified December 2013

Supersaturation and Precipitation of Diclofenac in the Stomach of Healthy Volunteers

2013/12/5 12:00

Condition: Supersaturation and Precipitation in the Stomach
Intervention: Drug: Diclofenac potassium 50 mg
Sponsor: Katholieke Universiteit Leuven
Not yet recruiting - verified December 2013

Effect of Proton Pump Inhibitors on CF Pulmonary Exacerbations

2013/11/6 12:00

Condition: Cystic Fibrosis
Intervention: Drug: esomeprazole
Sponsor: Columbia University
Completed - verified November 2013

Effect of Food and Increased Gastric pH Value on Bioavailability of a Single Dose of BI 207127 in Healthy Caucasian and Japanese Subjects

2013/11/5 12:00

Condition: Healthy
Interventions: Drug: BI 207127 high fat; Drug: BI 207127 with Omeprazole; Drug: BI 207127; Drug: BI 207127 low fat
Sponsor: Boehringer Ingelheim Pharmaceuticals
Recruiting - verified November 2013

ERADICATE Hp - Treating Helicobacter Pylori With RHB-105

2013/11/4 12:00

Conditions: Dyspepsia; Helicobacter Pylori Infection
Interventions: Drug: RHB-105; Drug: Placebo
Sponsor: RedHill Biopharma Limited
Recruiting - verified November 2013

BE Study Between a Capsule and a Sachet Formulation of D961H by Pharmacodynamics in Japanese Healthy Male Subjects

2013/10/14 12:00

Conditions: Gastric Ulcer; Duodenal Ulcer; Anastomotic Ulcer; Reflux Esophagitis; Etc.
Interventions: Drug: D961H sachet 20 mg; Drug: D961H HPMC capsule 20 mg
Sponsors: AstraZeneca; AstraZeneca
Not yet recruiting - verified October 2013

Prospective Study : Helicobacter Pylori Eradication Therapy in Accordance With Past Antibiotics Use

2013/9/5 12:00

Condition: Helicobacter Eradication
Intervention: Drug: Helicobacter pylori eradication
Sponsors: Ajou University School of Medicine; Ajou University School of Medicine
Not yet recruiting - verified September 2013

Drug-Drug Interaction Study With PF-05089771

2013/8/29 12:00

Condition: Healthy
Intervention: Drug: Pravastatin, midazolam, losartan, omeprazole, caffeine and PF-05089771
Sponsors: Pfizer; Pfizer
Not yet recruiting - verified August 2013

A Study of Baricitinib and Omeprazole in Healthy Participants

2013/8/15 12:00

Condition: Healthy Volunteers
Interventions: Drug: Baricitinib; Drug: Omeprazole
Sponsors: Eli Lilly and Company; Eli Lilly and Company
Not yet recruiting - verified August 2013

Eradication Rates of Helicobacter Pylori and Its Affecting Factors

2013/8/11 12:00

Condition: Helicobacter Infections
Intervention: Drug: PPI triple therapy
Sponsors: Seoul National University Bundang Hospital; Seoul National University Bundang Hospital
Completed - verified August 2013