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A Study to Evaluate the Safety and Antiviral Effect of ABT-450/Ritonavir and ABT-530 Coadministered With and Without Ribavirin in Adults With Genotype 3 Hepatitis C (HCV) Infection
2014/2/19 12:00
Conditions:   Chronic Hepatitis C;   Hepatitis C Virus
Interventions:   Drug: ABT-450/r;   Drug: ABT-530;   Drug: Ribavirin (RBV)
Sponsor:   AbbVie
Not yet recruiting - verified February 2013
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of TMC647055 in Combination With Ritonavir (Part 1) and the Co-administration of TMC435, TMC647055 and Ritonavir (Part 2) in Healthy Japanese Participants
2014/2/14 12:00
Condition:   Healthy
Interventions:   Drug: TMC647055;   Drug: TMC435;   Drug: Placebo;   Drug: Ritonavir (RTV)
Sponsor:   Janssen R&D Ireland
Not yet recruiting - verified February 2014
DDI Study of BMS-663068 With Etravirine (ETR) and/or Darunavir (DVR) + Ritonavir (RTV)
2014/2/13 12:00
Condition:   HIV/AIDS
Interventions:   Drug: BMS-663068;   Drug: Darunavir (DRV);   Drug: Ritonavir (RTV);   Drug: Etravirine (ETR)
Sponsor:   Bristol-Myers Squibb
Not yet recruiting - verified February 2014
Bioavailability of ABT-450 and ABT-267 With Ritonavir
2014/1/30 12:00
Condition:   Absolute Bioavailability
Intervention:   Drug: ABT-450/r/ABT-267
Sponsor:   AbbVie
Recruiting - verified January 2014
Microboosting of Atazanavir 300 mg With 50 mg Versus 100mg Ritonavir Daily in HIV-infected Patients: a Pharmacokinetic Study
2014/1/10 12:00
Condition:   HIV Infection
Intervention:   Drug: atazanavir 300mg boosted with ritonavir 50 mg
Sponsors:   Ottawa Hospital Research Institute;   Bristol-Myers Squibb
Recruiting - verified January 2014
Testing of HIV Protease Inhibitors to Suppress Inflammation and Improve Cardio Pulmonary Hemodynamics in Subjects With Pulmonary Arterial Hypertension
2013/12/23 12:00
Condition:   Pulmonary Arterial Hypertension
Interventions:   Drug: saquinavir and ritonavir;   Drug: saquinavir and ritonavir
Sponsors:   The Third Xiangya Hospital of Central South University;   Xiangya Hospital of Central South University
Recruiting - verified January 2013
Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT- 267 (ABT-450/r/ABT-267) in Japanese Adults With Subgenotype 1b Chronic Hepatitis C Virus (HCV) Infection
2013/12/23 12:00
Condition:   Hepatitis C Virus
Intervention:   Drug: ABT-450/r/ABT-267
Sponsor:   AbbVie
Recruiting - verified December 2013
Study to Evaluate the Efficacy and Safety of ABT-450/Ritonavir/ABT- 267 (ABT-450/r/ABT-267) in Japanese Adults With Genotype 2 Chronic Hepatitis C Virus (HCV) Infection
2013/12/23 12:00
Condition:   Hepatitis C Virus
Intervention:   Drug: ABT-450/r/ABT-267 plus Ribavirin
Sponsor:   AbbVie
Not yet recruiting - verified December 2013
Multicentre Study To Assess Changes In Bone Mineral Density Of The Switch From Protease Inhibitors To Dolutegravir In HIV-1-Infected Subjects With Low Bone Mineral Density
2013/10/7 12:00
Condition:   HIV-1 Infection
Interventions:   Drug: Dolutegravir, 50mg every 24 hours;   Drug: Protease Inhibitor/ritonavir
Sponsor:   Fundacio Lluita Contra la SIDA
Not yet recruiting - verified October 2013
A Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 Coadministered With Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 (HIV-1) Coinfection
2013/9/6 12:00
Conditions:   Hepatitis C Virus Infection;   Human Immunodeficiency Virus Infection;   Chronic Hepatitis C;   Compensated Cirrhosis and Non-cirrhotics
Interventions:   Drug: ABT-450/r/ABT-267;   Drug: ABT-333;   Drug: Ribavirin (RBV)
Sponsors:   AbbVie;   AbbVie
Recruiting - verified August 2013
LAAM-HAART PET Imaging
2013/8/30 12:00
Condition:   Healthy Volunteers
Interventions:   Radiation: [11c] LAAM;   Drug: Ritonavir;   Drug: Efavirenz
Sponsors:   Washington University School of Medicine;   Washington University School of Medicine
Recruiting - verified August 2013
Two Part Study to Study Pharmacokinetics, Safety, and Antiviral Activity of Elvitegravir (EVG) Administered With a PI/r Background Regimen for ARV Treatment-Experienced Pediatric Subjects
2013/8/9 12:00
Conditions:   Acquired Immune Deficiency Syndrome (AIDS);   HIV Infections
Interventions:   Drug: Elvitegravir;   Drug: Darunavir;   Drug: Lopinavir;   Drug: Atazanavir;   Drug: Tipranavir;   Drug: Fosamprenavir;   Drug: Ritonavir
Sponsors:   Gilead Sciences;   Gilead Sciences
Recruiting - verified August 2013
A Study to Determine Safety and Efficacy of Dolutegravir/Abacavir/Lamivudine (DTG/ABC/3TC) in Human Immunodeficiency Virus (HIV)-1 Infected Antiretroviral Therapy (ART) Naïve Women (ARIA)
2013/7/25 12:00
Condition:   Infection, Human Immunodeficiency Virus
Interventions:   Drug: Dolutegravir/abacavir/lamivudine FDC;   Drug: Atazanavir;   Drug: Ritonavir;   Drug: Tenofovir/emtricitabine FDC
Sponsors:   ViiV Healthcare;   ViiV Healthcare;   GlaxoSmithKline
Not yet recruiting - verified July 2013
Evaluating Pharmacokinetic Interactions With Vaginal Ring Contraceptives and ART
2013/7/16 12:00
Condition:   HIV-1 Infection
Interventions:   Device: Etonogestrel/ethinyl estradiol vaginal ring (NuvaRing);   Drug: Efavirenz;   Drug: Atazanavir/Ritonavir
Sponsors:   AIDS Clinical Trials Group;   AIDS Clinical Trials Group;   National Institute of Allergy and Infectious Diseases (NIAID)
Not yet recruiting - verified July 2013
Bone Mineral Density Changes in HIV-positive Females With Osteopenia Switching to Raltegravir
2013/7/10 12:00
Conditions:   HIV Infection;   Osteopenia
Interventions:   Drug: raltegravir and atazanavir and ritonavir;   Drug: tenofovir/emtricitabine and atazanavir and ritonavir
Sponsors:   University of Turin, Italy;   Giovanni Di Perri;   University of Turin, Italy;   University of Milan
Not yet recruiting - verified July 2013
The Interaction of Two HIV Medications With Blood Clot Medications in Healthy Volunteers
2013/7/6 12:00
Conditions:   HIV;   Atrial Fibrillation;   Venous Thromboembolism
Interventions:   Drug: Ritonavir;   Drug: Cobicistat
Sponsors:   National Institutes of Health Clinical Center (CC);   National Institutes of Health Clinical Center (CC);   National Institute of Allergy and Infectious Diseases (NIAID)
Recruiting - verified June 2013
A Study of Drug-drug Interaction Between Ritonavir and TMC435350 in Healthy Volunteers
2013/6/28 12:00
Condition:   Hepatitis C
Interventions:   Drug: TMC435350 200 mg;   Drug: Ritonavir 100 mg
Sponsors:   Tibotec Pharmaceuticals, Ireland;   Tibotec Pharmaceuticals, Ireland
Completed - verified June 2013
Mechanisms of Immune Reconstitution & Reduced Immune Activation Following Darunavir-based ART
2013/6/1 12:00
Condition:   Human Immunodeficiency Virus Infection
Intervention:   Drug: darunavir with ritonavir and fixed-dose viread+emtricitabine daily
Sponsors:   University of California, Davis;   David Asmuth, MD
Recruiting - verified June 2013
A Study to Evaluate the Efficacy and Safety of Three Experimental Drugs Compared With Telaprevir (a Licensed Product) for Treatment of Chronic Hepatitis C Infection in Treatment-experienced Adults
2013/5/13 12:00
Condition:   Chronic Hepatitis C Infection
Interventions:   Drug: ABT-450/r/ABT-267;   Drug: ABT-333;   Drug: Ribavrin;   Drug: Pegylated Interferon alpha 2-alpha (PegINF);   Drug: Telaprevir
Sponsors:   AbbVie;   AbbVie
Not yet recruiting - verified April 2013
Antiretroviral Regimens Containing Raltegravir for Prophylaxis of Mother-to-child-transmission of HIV Infection
2013/4/22 12:00
Conditions:   HIV;   Pregnancy
Interventions:   Drug: Raltegravir;   Drug: Lopinavir/Ritonavir
Sponsors:   Fundação Bahiana de Infectologia;   Fundação Bahiana de Infectologia
Not yet recruiting - verified May 2013