Condition:   Leukemia
Interventions:   Drug: Fludarabine;   Drug: Clofarabine;   Drug: Busulfan;   Drug: SAHA;   Procedure: Stem Cell Infusion (SCT);   Drug: Thymoglobulin
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified March 2014

Conditions:   Chronic Myeloid Leukemia (CML);   Acute Myelogenous Leukemia (AML);;   Myelodysplastic Syndrome (MDS);;   Juvenile Myelomonocytic Leukemia (JMML);;   Acute Lymphoblastic Leukemia (ALL);;   Lymphoma (Hodgkin's and Non-Hodgkin's)
Interventions:   Device: CliniMACS CD34+ Reagent System;   Drug: Thiotepa;   Drug: Cyclophosphamide;   Drug: Alemtuzumab;   Drug: Tacrolimus;   Drug: Melphalan;   Drug: Busulfan;   Drug: Fludarabine
Sponsors:   Columbia University;   Diane George, MD
Recruiting - verified February 2014

Condition:   Leukemia, Myeloid, Acute
Interventions:   Drug: busulfan;   Drug: fludarabine phosphate;   Radiation: total-body irradiation (TBI);   Procedure: allogeneic hematopoietic stem cell transplantation;   Drug: cyclophosphamide
Sponsor:   Washington University School of Medicine
Not yet recruiting - verified February 2014

Condition:   Allogeneic Haematopoietic Stem Cell Transplantation
Intervention:   Drug: Treosulfan
Sponsors:   Great Ormond Street Hospital for Children NHS Foundation Trust;   The Newcastle Upon Tyne Hospitals NHS Foundation Trust
Not yet recruiting - verified January 2014

Condition:   Genetic Rare Disease
Intervention:   Drug: Busulfan
Sponsor:   Seoul National University Hospital
Not yet recruiting - verified January 2014

Condition:   High-risk Medulloblastoma
Interventions:   Drug: Carboplatin + etoposide;   Drug: Thiotepa;   Drug: Cyclophosphamide + Busilvex
Sponsor:   Gustave Roussy, Cancer Campus, Grand Paris
Recruiting - verified December 2013

Conditions:   Leukemia;   Myelodysplasia;   Acute Lymphocytic Leukemia;   Acute Myelogenous Leukemia
Interventions:   Procedure: Umbilical Cord Blood Transfusion;   Drug: Fludarabine;   Drug: Busulfan;   Drug: Melphalan
Sponsor:   University of Miami Sylvester Comprehensive Cancer Center
Recruiting - verified December 2013

Conditions:   Advanced Cancers;   Lymphoma
Interventions:   Drug: Azacitidine;   Drug: Vorinostat;   Drug: Gemcitabine;   Drug: Busulfan;   Drug: Melphalan;   Drug: Dexamethasone;   Other: Caphosol;   Drug: Glutamine;   Drug: Pyridoxine;   Drug: Rituximab
Sponsor:   M.D. Anderson Cancer Center
Recruiting - verified November 2013

Conditions:   Blood And Marrow Transplantation;   Leukemia;   Lymphoma;   Transplantation Infection;   Myelodysplastic Syndrome (MDS);   Non-Hodgkin's Lymphoma (NHL);   Hodgkin's Lymphoma
Interventions:   Drug: Fludarabine, Clofarabine, Busulfan, ATG, TBI (Myeloablative);   Drug: Fludarabine, Melphalan, ATG (Reduced Intensity)
Sponsor:   Targazyme, Inc.
Active, not recruiting - verified November 2013

Conditions:   Myelodysplastic Syndrome;   Acute Myeloid Leukemia
Interventions:   Drug: BX2;   Drug: BX3;   Drug: BX4
Sponsor:   Institut Paoli-Calmettes
Not yet recruiting - verified November 2013

Conditions:   Bone Marrow Failure Syndrome;   Severe Aplastic Anemia;   Severe Congenital Neutropenia;   Amegakaryocytic Thrombocytopenia;   Diamond-Blackfan Anemia;   Schwachman Diamond Syndrome;   Primary Immunodeficiency Syndromes;   Acquired Immunodeficiency Syndromes;   Histiocytic Syndrome;   Familial Hemophagocytic Lymphocytosis;   Lymphohistiocytosis;   Macrophage Activation Syndrome;   Langerhans Cell Histiocytosis (LCH);   Hemoglobinopathies;   Sickle Cell Disease;   Sickle Cell-beta-thalassemia
Intervention:   Biological: CliniMacs (PLUS) Reagent System
Sponsors:   Columbia University;   Diane George, MD
Recruiting - verified October 2013

Conditions:   Adult Grade III Lymphomatoid Granulomatosis;   Adult Nasal Type Extranodal NK/T-cell Lymphoma;   Anaplastic Large Cell Lymphoma;   Angioimmunoblastic T-cell Lymphoma;   Childhood Burkitt Lymphoma;   Childhood Diffuse Large Cell Lymphoma;   Childhood Grade III Lymphomatoid Granulomatosis;   Childhood Immunoblastic Large Cell Lymphoma;   Childhood Nasal Type Extranodal NK/T-cell Lymphoma;   Contiguous Stage II Adult Burkitt Lymphoma;   Contiguous Stage II Adult Diffuse Large Cell Lymphoma;   Contiguous Stage II Adult Diffuse Mixed Cell Lymphoma;   Contiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma;   Contiguous Stage II Adult Immunoblastic Large Cell Lymphoma;   Contiguous Stage II Adult Lymphoblastic Lymphoma;   Contiguous Stage II Grade 1 Follicular Lymphoma;   Contiguous Stage II Grade 2 Follicular Lymphoma;   Contiguous Stage II Grade 3 Follicular Lymphoma;   Contiguous Stage II Mantle Cell Lymphoma;   Contiguous Stage II Marginal Zone Lymphoma;   Contiguous Stage II Small Lymphocytic Lymphoma;   Cutaneous B-cell Non-Hodgkin Lymphoma;   Extranodal Marginal Zone B-cell Lymphoma of Mucosa-associated Lymphoid Tissue;   Hepatosplenic T-cell Lymphoma;   Intraocular Lymphoma;   Nodal Marginal Zone B-cell Lymphoma;   Noncontiguous Stage II Adult Burkitt Lymphoma;   Noncontiguous Stage II Adult Diffuse Large Cell Lymphoma;   Noncontiguous Stage II Adult Diffuse Mixed Cell Lymphoma;   Noncontiguous Stage II Adult Diffuse Small Cleaved Cell Lymphoma;   Noncontiguous Stage II Adult Immunoblastic Large Cell Lymphoma;   Noncontiguous Stage II Adult Lymphoblastic Lymphoma;   Noncontiguous Stage II Grade 1 Follicular Lymphoma;   Noncontiguous Stage II Grade 2 Follicular Lymphoma;   Noncontiguous Stage II Grade 3 Follicular Lymphoma;   Noncontiguous Stage II Mantle Cell Lymphoma;   Noncontiguous Stage II Marginal Zone Lymphoma;   Noncontiguous Stage II Small Lymphocytic Lymphoma;   Noncutaneous Extranodal Lymphoma;   Peripheral T-cell Lymphoma;   Recurrent Adult Burkitt Lymphoma;   Recurrent Adult Diffuse Large Cell Lymphoma;   Recurrent Adult Diffuse Mixed Cell Lymphoma;   Recurrent Adult Diffuse Small Cleaved Cell Lymphoma;   Recurrent Adult Grade III Lymphomatoid Granulomatosis;   Recurrent Adult Hodgkin Lymphoma;   Recurrent Adult Immunoblastic Large Cell Lymphoma;   Recurrent Adult Lymphoblastic Lymphoma;   Recurrent Adult T-cell Leukemia/Lymphoma;   Recurrent Childhood Anaplastic Large Cell Lymphoma;   Recurrent Childhood Grade III Lymphomatoid Granulomatosis;   Recurrent Childhood Large Cell Lymphoma;   Recurrent Childhood Lymphoblastic Lymphoma;   Recurrent Childhood Small Noncleaved Cell Lymphoma;   Recurrent Cutaneous T-cell Non-Hodgkin Lymphoma;   Recurrent Grade 1 Follicular Lymphoma;   Recurrent Grade 2 Follicular Lymphoma;   Recurrent Grade 3 Follicular Lymphoma;   Recurrent Mantle Cell Lymphoma;   Recurrent Marginal Zone Lymphoma;   Recurrent Mycosis Fungoides/Sezary Syndrome;   Recurrent Small Lymphocytic Lymphoma;   Recurrent/Refractory Childhood Hodgkin Lymphoma;   Refractory Hairy Cell Leukemia;   Small Intestine Lymphoma;   Splenic Marginal Zone Lymphoma;   Stage I Adult Burkitt Lymphoma;   Stage I Adult Diffuse Large Cell Lymphoma;   Stage I Adult Diffuse Mixed Cell Lymphoma;   Stage I Adult Diffuse Small Cleaved Cell Lymphoma;   Stage I Adult Hodgkin Lymphoma;   Stage I Adult Immunoblastic Large Cell Lymphoma;   Stage I Adult Lymphoblastic Lymphoma;   Stage I Adult T-cell Leukemia/Lymphoma;   Stage I Childhood Anaplastic Large Cell Lymphoma;   Stage I Childhood Hodgkin Lymphoma;   Stage I Childhood Large Cell Lymphoma;   Stage I Childhood Lymphoblastic Lymphoma;   Stage I Childhood Small Noncleaved Cell Lymphoma;   Stage I Cutaneous T-cell Non-Hodgkin Lymphoma;   Stage I Grade 1 Follicular Lymphoma;   Stage I Grade 2 Follicular Lymphoma;   Stage I Grade 3 Follicular Lymphoma;   Stage I Mantle Cell Lymphoma;   Stage I Marginal Zone Lymphoma;   Stage I Small Lymphocytic Lymphoma;   Stage IA Mycosis Fungoides/Sezary Syndrome;   Stage IB Mycosis Fungoides/Sezary Syndrome;   Stage II Adult Hodgkin Lymphoma;   Stage II Adult T-cell Leukemia/Lymphoma;   Stage II Childhood Anaplastic Large Cell Lymphoma;   Stage II Childhood Hodgkin Lymphoma;   Stage II Childhood Large Cell Lymphoma;   Stage II Childhood Lymphoblastic Lymphoma;   Stage II Childhood Small Noncleaved Cell Lymphoma;   Stage II Cutaneous T-cell Non-Hodgkin Lymphoma;   Stage IIA Mycosis Fungoides/Sezary Syndrome;   Stage IIB Mycosis Fungoides/Sezary Syndrome;   Stage III Adult Burkitt Lymphoma;   Stage III Adult Diffuse Large Cell Lymphoma;   Stage III Adult Diffuse Mixed Cell Lymphoma;   Stage III Adult Diffuse Small Cleaved Cell Lymphoma;   Stage III Adult Hodgkin Lymphoma;   Stage III Adult Immunoblastic Large Cell Lymphoma;   Stage III Adult Lymphoblastic Lymphoma;   Stage III Adult T-cell Leukemia/Lymphoma;   Stage III Childhood Anaplastic Large Cell Lymphoma;   Stage III Childhood Hodgkin Lymphoma;   Stage III Childhood Large Cell Lymphoma;   Stage III Childhood Lymphoblastic Lymphoma;   Stage III Childhood Small Noncleaved Cell Lymphoma;   Stage III Cutaneous T-cell Non-Hodgkin Lymphoma;   Stage III Grade 1 Follicular Lymphoma;   Stage III Grade 2 Follicular Lymphoma;   Stage III Grade 3 Follicular Lymphoma;   Stage III Mantle Cell Lymphoma;   Stage III Marginal Zone Lymphoma;   Stage III Small Lymphocytic Lymphoma;   Stage IIIA Mycosis Fungoides/Sezary Syndrome;   Stage IIIB Mycosis Fungoides/Sezary Syndrome;   Stage IV Adult Burkitt Lymphoma;   Stage IV Adult Diffuse Large Cell Lymphoma;   Stage IV Adult Diffuse Mixed Cell Lymphoma;   Stage IV Adult Diffuse Small Cleaved Cell Lymphoma;   Stage IV Adult Hodgkin Lymphoma;   Stage IV Adult Immunoblastic Large Cell Lymphoma;   Stage IV Adult Lymphoblastic Lymphoma;   Stage IV Adult T-cell Leukemia/Lymphoma;   Stage IV Childhood Anaplastic Large Cell Lymphoma;   Stage IV Childhood Hodgkin Lymphoma;   Stage IV Childhood Large Cell Lymphoma;   Stage IV Childhood Lymphoblastic Lymphoma;   Stage IV Childhood Small Noncleaved Cell Lymphoma;   Stage IV Cutaneous T-cell Non-Hodgkin Lymphoma;   Stage IV Grade 1 Follicular Lymphoma;   Stage IV Grade 2 Follicular Lymphoma;   Stage IV Grade 3 Follicular Lymphoma;   Stage IV Mantle Cell Lymphoma;   Stage IV Marginal Zone Lymphoma;   Stage IV Small Lymphocytic Lymphoma;   Stage IVA Mycosis Fungoides/Sezary Syndrome;   Stage IVB Mycosis Fungoides/Sezary Syndrome;   T-cell Large Granular Lymphocyte Leukemia;   Testicular Lymphoma;   Waldenström Macroglobulinemia
Interventions:   Drug: busulfan;   Drug: etoposide;   Drug: cyclophosphamide;   Procedure: peripheral blood stem cell transplantation;   Procedure: autologous hematopoietic stem cell transplantation
Sponsors:   Case Comprehensive Cancer Center;   Case Comprehensive Cancer Center;   National Cancer Institute (NCI)
Not yet recruiting - verified October 2013

Condition:   Acute Lymphoblastic Leukaemia
Interventions:   Drug: VP16;   Radiation: TBI;   Drug: Thiotepa;   Drug: Treosulfan;   Drug: Fludarabine;   Drug: Busulfan
Sponsors:   St. Anna Kinderkrebsforschung;   St. Anna Kinderkrebsforschung;   Medical University of Graz;   Medical University Innsbruck
Recruiting - verified September 2013

Condition:   Multiple Myeloma
Interventions:   Drug: BUSULFEX®;   Drug: Alkeran®
Sponsors:   Chonnam National University Hospital;   Chonnam National University Hospital;   Korea Otsuka Pharmaceutical Co.,Ltd.
Recruiting - verified August 2013

Condition:   Multiple Myeloma
Interventions:   Drug: bortezomib (Velcade ®);   Drug: lenalidomide (Revlimid®);   Drug: busulfan (Busilvex ®);   Drug: Dexamethasone acetate;   Drug: Melphalan
Sponsors:   PETHEMA Foundation;   PETHEMA Foundation;   Janssen, LP;   Celgene Corporation;   Pierre Fabre Medicament
Recruiting - verified August 2013

Conditions:   Hematopoietic Stem Cell Transplantation;   Antithymocyte Globulin;   Viral Infection
Intervention:   Drug: ATG
Sponsors:   Nanfang Hospital of Southern Medical University;   Nanfang Hospital of Southern Medical University;   Peking University People's Hospital;   Guangxi Medical University;   Southern Medical University, China;   Guangzhou General Hospital of Guangzhou Military Command
Recruiting - verified June 2013

Conditions:   GATA2;   Immunodeficiency;   MDS
Interventions:   Drug: Fludarabine(Fludara, Berlex Laboratories);   Drug: Busulfan (Busulfex);   Drug: Sirolimus (Rapamune);   Drug: Cyclophosphamide(CTX, Cytoxan);   Drug: Methotrexate(Methotrexate Sodium, MTX, NSC-740);   Drug: Tacrolimus (FK506, Prograf);   Procedure: Total Body Irradiation (TBI);   Drug: Equine Anti-Thymocyte Globulin
Sponsors:   National Institutes of Health Clinical Center (CC);   National Cancer Institute (NCI)
Recruiting - verified April 2013

Condition:   Neuroblastoma
Interventions:   Drug: cyclophosphamide;   Drug: topotecan;   Biological: hu14.18K322A;   Procedure: peripheral blood stem cell harvest;   Procedure: surgical resection;   Drug: cisplatin;   Drug: etoposide;   Drug: doxorubicin;   Drug: vincristine;   Drug: busulfan;   Drug: melphalan;   Biological: peripheral blood stem cell transplantation;   Biological: natural killer cell infusion;   Radiation: radiation therapy;   Biological: GM-CSF;   Biological: G-CSF;   Drug: mesna;   Drug: levetiracetam;   Biological: interleukin-2;   Drug: Isotretinoin
Sponsors:   St. Jude Children's Research Hospital;   St. Jude Children's Research Hospital;   Cookies for Kids' Cancer
Not yet recruiting - verified May 2013

Condition:   Hematological Malignancy
Interventions:   Drug: Cohort 1-Bortezomib (Velcade ®);   Drug: Cohort 2-Bortezomib (Velcade ®);   Drug: Cohort 3-Bortezomib (Velcade ®)
Sponsors:   Spectrum Health Hospitals;   Spectrum Health Hospitals;   Millennium Pharmaceuticals, Inc.
Suspended - verified May 2013

Condition:   Adenosine Deaminase (ADA)-Deficient SCID
Intervention:   Genetic: EFS-ADA transduced CD34+ cells from the bone marrow
Sponsors:   University of California, Los Angeles;   Donald B. Kohn, M.D.;   National Institute of Allergy and Infectious Diseases (NIAID);   National Human Genome Research Institute (NHGRI)
Recruiting - verified May 2013