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药品详细

Nicotinamide (烟酰胺 )

化学结构式图
中文名
烟酰胺
英文名
Nicotinamide
分子式
Not Available
化学名
pyridine-3-carboxamide
分子量
Average: 122.1246
Monoisotopic: 122.048012824
CAS号
98-92-0
ATC分类
药物类型
small molecule
阶段
商品名
同义名
基本介绍

An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake. [PubChem]

生产厂家
    封装厂家
    参考
    Synthesis Reference Not Available
    General Reference Not Available
    剂型
    规格
    化合物类型
    Type small molecule
    Classes Not Available
    Substructures Not Available
    适应症
    Diabetes 糖尿病;
    药理
    Indication Not Available
    Pharmacodynamics Not Available
    Mechanism of action Not Available
    Absorption Not Available
    Volume of distribution Not Available
    Protein binding Not Available
    Metabolism
    Route of elimination Not Available
    Half life Not Available
    Clearance Not Available
    Toxicity Not Available
    Affected organisms Not Available
    Pathways Not Available
    理化性质
    Properties
    State solid
    Melting point 130 oC
    Experimental Properties
    Property Value Source
    water solubility 500 mg/mL at 25 oC [MERCK INDEX (1996)] PhysProp
    logP -0.37 [HANSCH,C ET AL. (1995)] PhysProp
    logS 0.61 [ADME Research, USCD] PhysProp
    Predicted Properties
    Property Value Source
    water solubility 5.01e+01 g/l ALOGPS
    logP -0.45 ALOGPS
    logP -0.39 ChemAxon Molconvert
    logS -0.39 ALOGPS
    pKa ChemAxon Molconvert
    hydrogen acceptor count 2 ChemAxon Molconvert
    hydrogen donor count 1 ChemAxon Molconvert
    polar surface area 55.98 ChemAxon Molconvert
    rotatable bond count 1 ChemAxon Molconvert
    refractivity 32.98 ChemAxon Molconvert
    polarizability 11.71 ChemAxon Molconvert
    药物相互作用
    食物相互作用
    Not Available

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