药品详细
Aluminium(铝)
化学结构式图
中文名
铝
英文名
Aluminium
分子式
Al
化学名
alumane
分子量
Average: 26.9815386
Monoisotopic: 26.981538441
Monoisotopic: 26.981538441
CAS号
7429-90-5
ATC分类
A02A 未知;A02A 未知;C10A 未知;D10A Anti-Acne Preparations for Topical Use;C10A 未知;C05A 未知;A01A 未知;A02A 未知;M05B 未知;D09A 未知;D10A Anti-Acne Preparations for Topical Use;A02A 未知;S02A 未知
药物类型
small molecule
阶段
approved
商品名
同义名
基本介绍
A metallic element that has the atomic number 13, atomic symbol Al, and atomic weight 26.98. [PubChem]
生产厂家
封装厂家
参考
| Synthesis Reference | Not Available |
| General Reference | Not Available |
剂型
规格
化合物类型
| Type | small molecule |
| Classes |
|
| Substructures |
|
适应症
药理
| Indication | Not Available |
| Pharmacodynamics | Not Available |
| Mechanism of action | Aluminum Acetate is an astringent. An astrignent is a chemical that tends to shrink or constrict body tissues, usually locally after topical medicinal application. The shrinkage or constriction is through osmotic flow of water (or other fluids) away from the area where the astringent was applied. Astringent medicines cause shrinkage of mucous membranes or exposed tissues and are often used internally to check discharge of blood serum or mucous secretions. This can happen with a sore throat, hemorrhages, diarrhea, or with peptic ulcers. Externally applied astringents, which cause mild coagulation of skin proteins, dry, harden, and protect the skin. Acne sufferers are often advised to use astringents if they have oily skin. Astringents also help heal stretch marks and other scars. Mild astringent solutions are used in the relief of such minor skin irritations as those resulting from superficial cuts, allergies, insect bites, or fungal infections such as athlete's foot. |
| Absorption | Not Available |
| Volume of distribution | Not Available |
| Protein binding | Not Available |
| Metabolism |
Not Available
|
| Route of elimination | Not Available |
| Half life | Not Available |
| Clearance | Not Available |
| Toxicity | Not Available |
| Affected organisms | Not Available |
| Pathways | Not Available |
理化性质
| Properties | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| State | solid | |||||||||||||||||||||||||||
| Experimental Properties |
|
|||||||||||||||||||||||||||
| Predicted Properties |
|
|||||||||||||||||||||||||||
药物相互作用
| Drug | Interaction |
|---|---|
| Amprenavir | The antiacid decreases the absorption of amprenavir |
| Atazanavir | This gastric pH modifier decreases the levels/effects of atazanavir |
| Chloroquine | The antiacid decreases the absorption of chloroquine |
| Ciprofloxacin | Formation of non-absorbable complexes |
| Clindamycin | The aluminium salt decreases the absorption of lincosamides |
| Clodronate | Formation of non-absorbable complexes |
| Dapsone | Formation of non-absorbable complexes |
| Deferasirox | Possible physicochemical interaction |
| Delavirdine | The antiacid decreases the effect of delavirdine |
| Demeclocycline | Formation of non-absorbable complexes |
| Doxycycline | Formation of non-absorbable complexes |
| Etidronic acid | Formation of non-absorbable complexes |
| Fosamprenavir | The antiacid decreases the absorption of amprenavir |
| Gatifloxacin | Formation of non-absorbable complexes |
| Gemifloxacin | Formation of non-absorbable complexes |
| Grepafloxacin | Formation of non-absorbable complexes |
| Ibandronate | Formation of non absorbable complexes |
| Indinavir | The antacid decreases the absorption of indinavir |
| Itraconazole | Aluminum-containing antacids may decrease the effect of itraconazole. |
| Ketoconazole | Aluminum-containing antacids may decrease the effect of ketoconazole. |
| Levofloxacin | Formation of non-absorbable complexes |
| Lincomycin | The aluminium salt decreases the absorption of lincosamides |
| Minocycline | Formation of non-absorbable complexes |
| Moxifloxacin | Formation of non-absorbable complexes |
| Norfloxacin | Formation of non-absorbable complexes |
| Ofloxacin | Formation of non-absorbable complexes |
| Penciclovir | The multivalent agent decreases the effect of penicillamine |
| Polystyrene sulfonate | Risk of alkalosis in renal impairment |
| Tetracycline | Formation of non-absorbable complexes |
| Trovafloxacin | Aluminum may decrease the absorption of orally administered Trovafloxacin. Administer Trovafloxacin 2 hours before or 6 hours after a dose of the aluminum containing agent to minimize the interaction. |
食物相互作用
Not Available
收藏