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药品详细

Bentoquatam(本托奎坦)

化学结构式图
中文名
本托奎坦
英文名
Bentoquatam
分子式
Al2H2O6Si
化学名
oxo[(oxoalumanyl)oxy]alumane silanedione hydrate
分子量
Average: 180.0609
Monoisotopic: 179.925141211
CAS号
1340-69-8
ATC分类
药物类型
small molecule
阶段
approved
商品名
同义名
基本介绍

Bentoquatam is a topical medication intended to act as a shield against exposure to the irritating substance urushiol, found in plants such as poison ivy or poison oak. Bentoquatam contains bentonite, a clay, and is only effective as long as the film is visible on the skin.

生产厂家
  • Standard homeopathic co
封装厂家
参考
Synthesis Reference Not Available
General Reference
  1. Scott MJ, Heumann MA, DeBruyckere DM, Brundage TW, Kohn MA: The feasibility of using skin protectant products and education to prevent poison oak. Wilderness Environ Med. 2002 Fall;13(3):206-8. Pubmed
剂型
规格
化合物类型
Type small molecule
Classes
  • Inorganic Ions and Gases
Substructures
  • Inorganic Ions and Gases
适应症
药理
Indication Used to prevent or reduce the severity of allergic contact dermatitis due to urushiol, the allergenic resin of poison ivy, poison oak, and poison sumac.
Pharmacodynamics Bentoquatam protects the skin like a shield against poison ivy, poison oak, and poison sumac by physically blocking skin contact with their resin. The best protection against getting these conditions is to avoid contact with these plants. This medicine does not dry oozing and weeping caused by the rash of poison ivy, poison oak, or poison sumac.
Mechanism of action The mechanism of action is unknown. It is thought topically applied bentoquatam acts as a physical barrier that interferes with the adsorption of antigens onto the skin and reduces absorption of antigens into the skin. It probably does not work by modifying the systemic allergic response.
Absorption Not Available
Volume of distribution Not Available
Protein binding Not Available
Metabolism
Not Available
Route of elimination Not Available
Half life Not Available
Clearance Not Available
Toxicity Rare side effects include mild erythema (mild redness of skin).
Affected organisms
  • Humans and other mammals
Pathways Not Available
理化性质
Properties
State solid
Experimental Properties
Property Value Source
water solubility Soluble Not Available
Predicted Properties
Property Value Source
logP 2.47 ChemAxon
pKa (strongest basic) -3 ChemAxon
physiological charge 0 ChemAxon
hydrogen acceptor count 2 ChemAxon
hydrogen donor count 0 ChemAxon
polar surface area 43.37 ChemAxon
rotatable bond count 2 ChemAxon
refractivity 4.24 ChemAxon
polarizability 6.44 ChemAxon
药物相互作用
食物相互作用
Not Available

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