药品详细
Potassium Iodide(碘化钾)
化学结构式图
中文名
碘化钾
英文名
Potassium Iodide
分子式
IK
化学名
potassium iodide
分子量
Average: 166.0028
Monoisotopic: 165.868175281
Monoisotopic: 165.868175281
CAS号
7681-11-0
ATC分类
V03A 未知;S01X 其他眼科用药;R05C 未知
药物类型
small molecule
阶段
approved
商品名
同义名
基本介绍
Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.
生产厂家
- Anbex inc
- Fleming and co pharmaceuticals
- Medpointe pharmaceuticals medpointe healthcare inc
- Recip ab
- Roxane laboratories inc
封装厂家
参考
Synthesis Reference | Not Available |
General Reference | Not Available |
剂型
规格
化合物类型
Type | small molecule |
Classes | Not Available |
Substructures | Not Available |
适应症
药理
Indication | Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution. |
Pharmacodynamics | It works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms. |
Mechanism of action | Not Available |
Absorption | Not Available |
Volume of distribution | Not Available |
Protein binding | Not Available |
Metabolism |
Not Available
|
Route of elimination | Not Available |
Half life | Not Available |
Clearance | Not Available |
Toxicity | Not Available |
Affected organisms | Not Available |
Pathways | Not Available |
理化性质
Properties | ||||||||||||||||||||||||||||
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State | solid | |||||||||||||||||||||||||||
Experimental Properties | Not Available | |||||||||||||||||||||||||||
Predicted Properties |
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药物相互作用
食物相互作用
Not Available