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药品详细

Potassium Iodide(碘化钾)

化学结构式图
中文名
碘化钾
英文名
Potassium Iodide
分子式
IK
化学名
potassium iodide
分子量
Average: 166.0028
Monoisotopic: 165.868175281
CAS号
7681-11-0
ATC分类
V03A 未知;S01X 其他眼科用药;R05C 未知
药物类型
small molecule
阶段
approved
商品名
同义名
基本介绍

Saturated solution of Potassium Iodide (SSKI) is used pharmaceutically for emergency use in patients experiencing acute symptoms of severe hyperglycemia (also known as thyroid storm or thyrotoxic crisis). SSKI can also be used for radioiodine-contamination emergencies or in preparation of thyrotoxic patients for thyroidectomy.

生产厂家
  • Anbex inc
  • Fleming and co pharmaceuticals
  • Medpointe pharmaceuticals medpointe healthcare inc
  • Recip ab
  • Roxane laboratories inc
封装厂家
参考
Synthesis Reference Not Available
General Reference Not Available
剂型
规格
化合物类型
Type small molecule
Classes Not Available
Substructures Not Available
适应症
药理
Indication Potassium Iodide is oral antithyroid agent. Potassium Iodide is used as an adjunct to other antithyroid agents in the treatment of hyperthyroidism and thyrotoxicosis and preoperatively to induce thyroid involution.
Pharmacodynamics It works in the thyroid gland. By inhibiting thyroid hormone synthesis and release, thyroid gland vascularity is reduced, thyroid gland tissue becomes firmer, thyroid cell size is reduced, follicular colloid reaccumulates, and bound iodine levels increase. As a protectant following radiation exposure, KI blocks the uptake of radioactive iodine isotopes by the thyroid gland thereby minimizing the risk of radiation-induced thyroid neoplasms.
Mechanism of action Not Available
Absorption Not Available
Volume of distribution Not Available
Protein binding Not Available
Metabolism
Not Available
Route of elimination Not Available
Half life Not Available
Clearance Not Available
Toxicity Not Available
Affected organisms Not Available
Pathways Not Available
理化性质
Properties
State solid
Experimental Properties Not Available
Predicted Properties
Property Value Source
logP 0.2 ChemAxon
physiological charge 1 ChemAxon
hydrogen acceptor count 0 ChemAxon
hydrogen donor count 0 ChemAxon
polar surface area 0 ChemAxon
rotatable bond count 0 ChemAxon
refractivity 0 ChemAxon
polarizability 1.78 ChemAxon
药物相互作用
食物相互作用
Not Available

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