药品详细
Phenazopyridine(那吡啶)
化学结构式图
中文名
那吡啶
英文名
Phenazopyridine
分子式
C11H11N5
化学名
3-[(E)-2-phenyldiazen-1-yl]pyridine-2,6-diamine
分子量
Average: 213.2385
Monoisotopic: 213.101445377
Monoisotopic: 213.101445377
CAS号
94-78-0
ATC分类
G04B 未知
药物类型
small molecule
阶段
approved
商品名
同义名
基本介绍
A local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity. [PubChem]
生产厂家
封装厂家
- Advanced Pharmaceutical Services Inc.
- Amerifit Inc.
- Amerisource Health Services Corp.
- Amkas Laboratories Inc.
- Amneal Pharmaceuticals
- Apotheca Inc.
- A-S Medication Solutions LLC
- Atlantic Biologicals Corporation
- Belgomex Sprl
- Boca Pharmacal
- Breckenridge Pharmaceuticals
- Bryant Ranch Prepack
- Comprehensive Consultant Services Inc.
- Consumers Choice
- Contract Pharm
- Corepharma LLC
- CVS Pharmacy
- Direct Dispensing Inc.
- Dispensing Solutions
- Diversified Healthcare Services Inc.
- Edwards Pharmaceuticals
- Group Health Cooperative
- H.J. Harkins Co. Inc.
- Johnson & Johnson Healthcare
- Kaiser Foundation Hospital
- Lehigh Valley Technologies Inc.
- Liberty Pharmaceuticals
- Lil' Drug Store
- Major Pharmaceuticals
- Mckesson Corp.
- Murfreesboro Pharmaceutical Nursing Supply
- Nucare Pharmaceuticals Inc.
- Patient First Corp.
- PCA LLC
- PD-Rx Pharmaceuticals Inc.
- Pharmedix
- Pharmelle LLC
- Physicians Total Care Inc.
- Preferred Pharmaceuticals Inc.
- Prepackage Specialists
- Prepak Systems Inc.
- Prescript Pharmaceuticals
- Rebel Distributors Corp.
- Redpharm Drug
- Rekah Pharmaceutical Industry Ltd.
- Remedy Repack
- Resource Optimization and Innovation LLC
- Scruggs Pharmacal Co. Inc.
- Southwood Pharmaceuticals
- Spectrum Pharmaceuticals
- St Mary's Medical Park Pharmacy
- Sunrise Pharmaceutical Inc.
- Superior Pharmeceuticals
- Tya Pharmaceuticals
- Warner Chilcott Co. Inc.
- WC Pharmaceuticals
参考
| Synthesis Reference | Not Available |
| General Reference | Not Available |
剂型
规格
化合物类型
| Type | small molecule |
| Classes |
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| Substructures |
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适应症
药理
| Indication | For the symptomatic relief of pain, burning, urgency, frequency, and other discomforts arising from irritation of the lower urinary tract mucosa caused by infection, trauma, surgery, endoscopic procedures, or the passage of sounds or catheters. | ||||||||
| Pharmacodynamics | Phenazopyridine is a local anesthetic that has been used in urinary tract disorders. Its use is limited by problems with toxicity (primarily blood disorders) and potential carcinogenicity. | ||||||||
| Mechanism of action | Phenazopyridine's mechanism of action is not well known, and only basic information on its interaction with the body is available. It is known that the chemical has a direct topical analgesic effect on the mucosa lining of the urinary tract. | ||||||||
| Absorption | Not Available | ||||||||
| Volume of distribution | Not Available | ||||||||
| Protein binding | Not Available | ||||||||
| Metabolism |
Likely hepatic but also in other tissues. One of the metabolites is acetaminophen.
Important The metabolism module of DrugBank is currently in beta. Questions or suggestions? Please contact us.
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| Route of elimination | 40% hepatic | ||||||||
| Half life | 7.35 hours | ||||||||
| Clearance | Not Available | ||||||||
| Toxicity | Methemoglobinemia generally follows a massive, acute overdose. | ||||||||
| Affected organisms |
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| Pathways | Not Available | ||||||||
理化性质
| Properties | |||||||||||||||||||||||||||||||||||||||||||
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| State | solid | ||||||||||||||||||||||||||||||||||||||||||
| Experimental Properties |
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| Predicted Properties |
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药物相互作用
食物相互作用
- Take with food to reduce irritation.
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