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药品详细

Pipazethate(Pipazethate)

化学结构式图
中文名
Pipazethate
英文名
Pipazethate
分子式
C21H25N3O3S
化学名
2-[2-(piperidin-1-yl)ethoxy]ethyl 9-thia-2,4-diazatricyclo[8.4.0.0^{3,8}]tetradeca-1(10),3,5,7,11,13-hexaene-2-carboxylate
分子量
Average: 399.507
Monoisotopic: 399.161662371
CAS号
2167-85-3
ATC分类
R05D 未知
药物类型
small molecule
阶段
approved
商品名
同义名
基本介绍

A non-narcotic oral antitussive agent.

生产厂家
    封装厂家
    参考
    Synthesis Reference Not Available
    General Reference Not Available
    剂型
    规格
    化合物类型
    Type small molecule
    Classes Not Available
    Substructures Not Available
    适应症
    药理
    Indication For the treatment of cough.
    Pharmacodynamics Antitussive agents act centrally on the medullary cough center.
    Mechanism of action Not Available
    Absorption Not Available
    Volume of distribution Not Available
    Protein binding Not Available
    Metabolism
    Not Available
    Route of elimination Not Available
    Half life Not Available
    Clearance Not Available
    Toxicity Not Available
    Affected organisms
    • Humans and other mammals
    Pathways Not Available
    理化性质
    Properties
    State solid
    Experimental Properties Not Available
    Predicted Properties
    Property Value Source
    water solubility 4.15e-02 g/l ALOGPS
    logP 3.4 ALOGPS
    logP 3.77 ChemAxon
    logS -4 ALOGPS
    pKa (strongest basic) 8.96 ChemAxon
    physiological charge 1 ChemAxon
    hydrogen acceptor count 5 ChemAxon
    hydrogen donor count 0 ChemAxon
    polar surface area 54.9 ChemAxon
    rotatable bond count 7 ChemAxon
    refractivity 111.43 ChemAxon
    polarizability 42.86 ChemAxon
    药物相互作用
    食物相互作用
    Not Available

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