专利详细信息
专利号 | CA2535060C |
专利标题 | Osmotic delivery of therapeutic compounds by solubility enhancement |
专利权人 | Shire Laboratories Inc.; |
发明人 | Kidane, Argaw;Ray, Shimul K;Bhatt, Padmanabh P;Bryan, Jones W Jr; |
申请号 | CA20042535060 |
申请日 | 2004/9/7 |
公开日 | 2013/11/5 |
优先权号 | |
IPC | A61K00924000; |
专利类型 | |
法律状态查询 | 查看法律状态 |
The present invention is directed to the oral osmotic delivery of therapeutic compounds that have limited solubility in an aqueous environment due to inherent hydrophobicity or to saturation limitations in the core of the osmotic system. The present invention is suitable for the osmotic delivery of glipizide and other hydrophobic drugs but runs the spectrum to other therapeutic agents with higher aqueous solubilities yet having a solubility limitation in an osmotic dosage unit due to high drug load.
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