The invention provides the drug products that contains the low dosage pioglitazone that is used for the treatment of Alzheimer type cognitive disorder (for example delayed onset).Its preparation method also is provided.Also be provided for treating the method for Alzheimer it comprises that administration has the drug products of low dosage pioglitazone.The method can comprise determines whether the curee exists the risk that develops into Alzheimer based on curee's age and TOMM40 523 genotype.

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