专利详细信息
专利号 | EA3025B1 |
专利标题 | Treatment of diabetes with thiazolidinedione and sulphonylures |
专利权人 | SMITHKLINE BEECHAM PLC; |
发明人 | Smith, Stephen Alistair; |
申请号 | |
申请日 | |
公开日 | 2002/12/26 |
优先权号 | |
IPC | A61K04500000; |
专利类型 | |
法律状态查询 | 查看法律状态 |
1. A method for the treatment of diabetes mellitus and conditions associated with diabetes mellitus in a mammal with positive effect by glycemic control without observable unfavourable effects which method comprises administering 2 to 12 mg daily 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-24-dione (Compound I) or a pharmaceutically acceptable salt thereof and sulfonyl urea. 2. A method according to Claim 1 wherein the c is glibenclamide glipizide gliclazide glimepiride tolazamide or tolbutamide. 3. A method according to any one of Claims 1 or 2 wherein the sulfonyl urea is glimepiride. 4. A method according to any one of Claims 1 to 4 which comprises the administration of 2 to 4 or 4 to 8 or 8 to 12 mg of Compound (I). 5. A method according to any one of Claims 1 to 4 which comprises the administration of 2 to 4 mg of Compound (I). 6. A method according to any one of Claims 1 to 4 which comprises the administration of 4 to 8 mg of Compound (I). 7. A method according to any one of Claims 1 to 4 which comprises the administration of 8 to 12 mg of Compound (I). 8. A method according to any one of Claims 1 to 4 which comprises the administration of 2 mg of Compound (I). 9. A method according to any one of Claims 1 to 4 which comprises the administration of 4 mg of Compound (I). 10. A method according to any one of Claims 1 to 4 which comprises the administration of 8 mg of Compound (I).
没有相关的数据
没有相关的数据
暂无附图
注:除CN专利外,本系统默认提供的所有其他中文标题和摘要来自机器翻译。