专利详细信息
| 专利号 |
 |
| 专利标题 | Pharmaceutical formulation comprising metformin and repaglinide |
| 专利权人 | Novo Nordisk A/s; |
| 发明人 | Hoejgaard, Bent;Knudsen, Breian;Rasmussen, Stella Rudkjaer;Jacobsen, Lene Orup; |
| 申请号 | US14/079127 |
| 申请日 | 2013/11/13 |
| 公开日 | 2014/3/6 |
| 优先权号 | |
| IPC | A61K03145100; |
| 专利类型 | |
| 法律状态查询 | 查看法律状态 |
The invention is related to a pharmaceutical composition comprising repaglinide in combination with metformin or a salt thereof in unit dosage form wherein a pre-formulation of the repaglinide has a pH independent dissolution profile and a relative humidity of less than about 25% prior to mixing with the metformin or a salt thereof; and optionally one or more pharmaceutically acceptable excipients and to a method for its preparation.
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