The use of ejaculatory-enhancing agents to treat males having low sperm counts to promote fertilization of an ovum. The ejaculatory-enhancing agents are used to promote more frequent ejaculations thus producing more sperm thus increasing the chance for the ovum to be fertilized because more sperm are available. The fertilization of the ovum can be by sexual intercourse with a female or by in vitro or artificial insemination fertilization. Examples of ejaculatory enhancing agents are dopamine receptor agonists specific phosphodiesterase-5 (PDE-V) inhibitors organic nitrates L-arginine and combinations thereof. The dopamine receptor agonists include apomorphine a pharmaceutically acceptable addition salt of apomorphine a derivative of apomorphine bromocriptine ropinirole cabergoline pramipexole roxindole and lisuride. Examples of PDE-V inhibitors include sildenafil tadalafil and vardenafil. Examples of organic nitrates include glycerol trinitrate amyl nitrite isosorbide dinitrate isosorbide-5-mononitrate and erythrityl tetranitrate.

暂无附图