The invention discloses a kind of synthetic method of gliclazide important intermediate particularly the synthetic method of N-amino-3-azabicyclo [330] octane hydrochloride.N-amino-3-azabicyclo [330] octane hydrochloride is by N-nitroso-group-3-azabicyclo [330] behind extraction the technical hydrochloric acid acidifying salify such as octane toluene free through zinc powder and hydrochloric acid reduction potassium hydroxide or sodium hydroxide alkalization or dimethylbenzene reduced-pressure backflow divides water to the greatest extent crystallisation by cooling and get final product.Technique of the present invention is simple and alkali charge is few and waste discharge is few and yield is high and cost is low and the energy coproduction is as the zinc hydroxide of rubber and surgery ointment auxiliary.The present invention is applicable to suitability for industrialized production.

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