The invention discloses a kind of dual control and release Gliclazide slow release capsule and preparation method thereof.The content of filling in the described slow releasing capsule is covered with the Gliclazide delayed-release micropill of rapid release film coating for the surface in 1000 capsules Gliclazide delayed-release micropill is wherein made by the raw material of following weight proportioning: gliclazide 20～30 microcrystalline Cellulose 30～50 lactose 40～60 hypromellose 4000cp 2～8 water 30～60; Rapid release film coating is made by the raw material of following weight proportioning: gliclazide 5～20 EudragitRL100 10～40 Pulvis Talci 5～30 volumetric concentration are 95% ethanol 300.Compared with prior art capsule of the present invention can also be brought into play the advantage of multiple-unit preparation when satisfying the rapid onset of medicine and keeping certain blood drug level and its preparation method is simple and easy to control.

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