The invention relates to ranitidine freeze-dried powder injection for curing gastropathy in particular to a medicine composition. The powder injection comprises ranitidine freeze-dry excipient and optional PH modifier wherein the freeze-dry excipient is selected from mannitol lactose cane sugar glucose sorbitol glycine dextran salt and the combinations thereof. The medicine composition comprises the following materials by 100 weight parts of ranitidine: 20-200 parts of freeze-dry excipient. The medicine composition is dissolved and diluted by water to an extent that 20 mg ranitidine is contained in the solution of 1ml and the pH value of the solution is 4.5-6.5. The medicine composition has the advantages of superior pharmaceutical characters including favorable chemical stability.

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