The invention discloses a kind of gliclazid in tablets (II) and preparation method thereof.This gliclazid in tablets (II) prescription contains 30%-60% gliclazide 30%-60% filler 1%-10% release regulator and 2%-20% framework material described percentage ratio accounts for the mass percent of gliclazid in tablets (II) total amount for each composition described filler is one or more in mannitol sorbitol xylitol lactose sucrose glucose starch dextrin pregelatinized Starch and the microcrystalline Cellulose; Described release regulator is one or more in carboxymethyl starch sodium polyvinylpolypyrrolidone hyprolose and the microcrystalline Cellulose; Described framework material is one or more in hydroxypropyl emthylcellulose ethyl cellulose carbomer sodium alginate and the stearic acid; Described gliclazid in tablets (II) also contains lubricant.This product is taken the interior gliclazide haemoconcentration of rear body and is kept for a long time debita spissitudo is difficult for causing hypoglycemia greatly improves Compliance and medicining times is moderate.

暂无附图