专利详细信息
专利号 | CN103641882A |
专利标题 | Oleanolic acid and preparation method thereof and the application in preparing glycosidase inhibitor fall in new 2,3 dihydroxyl-30- |
专利权人 | |
发明人 | |
申请号 | CN20131648211 |
申请日 | 2013/12/4 |
公开日 | 2014/3/19 |
优先权号 | |
IPC | C07J06300000; |
专利类型 | |
法律状态查询 | 查看法律状态 |
The invention discloses new 23 dihydroxyl-30-and fall Oleanolic Acid and preparation method thereof and the application in preparing glycosidase inhibitor.The present invention extracts separated potent a-glucosidase inhibitor from Three Akebia Decne Species and plant origin is abundant.And when adopting fruit to extract also can make plant itself be utilized for a long time without destruction can increase economic efficiency environmentally friendly again.Pharmacological evaluation shows compound 2 olea-12 fall in 3-dihydroxyl-23-aldehyde radical-30- the external a-Glucosidase inhibitor specific activity one line diabetes medicament acarbose of 20 (29)-diene-28-acid is stronger the medicine that is expected to be further development of prevention and treatment type II diabetes has good application and development potential quality.
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