The invention provides a kind of Lansoprazole composition freeze-dried powder pin relate to medicine and medicine manufacture technology field comprise following weight portion material composition: 1.75～2.14 parts of lansoprazoles 0.87～1.07 part of chitosan nano 96.80～97.38 parts of waters for injection.Advantage of the present invention is: in 1:0.5(lansoprazole: the half-life that the compositions that chitosan nano) ratio forms can significant prolongation medicine the action time of prolong drug improve the bioavailability of medicine and reduce the access times of patient's medicine; Experiment in vitro has been investigated the stability that Lansoprazole composition lyophilized formulations keeps sample in test in influence factor's test accelerated test and room temperature and result will be stablized compared with the Lansoprazole for injecting of single component.Take mice and rabbit as subjects lansoprazole freeze-dried lipidosome injection has been carried out to safety investigation result shows Lansoprazole for injecting freeze-dried composition nonirritant and apyrogeneity without haemolysis meets intravenous injection requirement.

暂无附图