The present invention relates to the field of bacteriology. In particular the present invention provides compositions (e.g. comprising a lantibiotic and mupirocin or gentamicin) and methods of treating (e.g. killing or inhibiting growth of) bacteria. For example the present invention provides pharmaceutical compounds (e.g. comprising a lantibiotic and mupirocin or gentamicin) and methods of using the same in research therapeutic and drug screening applications.

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