The invention provides a kind of process for purification that can obtain the high purity ceforanide with the reaction of ceforanide crude product and dicyclohexyl amine utilize impurity 3-[(1-carboxymethyl in the crude product) tetrazole-5-sulfydryl] methyl-7-amino-4-Cephalosporanic acid (ceforanide intermediate A CATAA) dicyclohexyl amine salt makes with extra care the extraordinarily thick product of cephalo thunder with ceforanide dicyclohexyl amine salt different solubility in organic solvent-aqueous solution.Ceforanide process for purification of the present invention has avoided toxicity very large the arylamine class material N that carinogenicity is very strong the use of accelerine make ceforanide purity from 70 ~ 85% of crude product bring up to after refining more than 99.5% purity improves greatly yield is better and starting material are easy to get and is convenient to the realization of ceforanide suitability for industrialized production.

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