Polymers (i.e. polyesters polyamides polythioesters polyanhydrides or a mixture thereof) which degrade hydrolytically to provide a combination of a beta-lactam antibiotic (e.g. amoxicillin) and a beta-lactamase inhibitor (e.g. clavulanic acid) (or a pharmaceutically acceptable salt thereof) are provided. Methods of producing these polymers intermediates useful for preparing these polymers and methods of using these polymers to deliver a combination of a beta-lactam antibiotic and a beta-lactamase inhibitor (or a pharmaceutically acceptable salt thereof) to a host are also provided.

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