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专利详细信息
专利号
US2013225598A1
专利标题 Stabilized Amorphous Forms of Imatinib Mesylate
专利权人 GONCALVES ELISABETE [CH];KALB OSKAR [CH];MUTZ MICHAEL [DE];WIRTH WOLFGANG [CH];LAKSHMAN JAY PARTHIBAN [US];NOVARTIS AG [CH];
发明人 GONCALVES ELISABETE [CH];KALB OSKAR [CH];MUTZ MICHAEL [DE];WIRTH WOLFGANG [CH];LAKSHMAN JAY PARTHIBAN [US];
申请号 US201313864888
申请日 2013/4/17
公开日 2013/8/29
优先权号
IPC A61K31/506; A61K47/02; A61K47/10; A61K47/32; A61K47/34; A61K47/38;
专利类型
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The invention relates to the stabilized amorphous form of the methanesulfonic acid addition salt of 4-(4-methylpiperazin-1-ylmethyl)-N-[4-methyl-3-(4-(pyridin-3-yl)-pyrimidin-2-ylamino)-pheny]-benzamide, pharmaceutical compositions such as capsules or tablets containing this form, the use of such form in diagnostic methods or, preferably, for the therapeutic treatment of warm-blooded animals, especially humans, and the use of formulation principles stabilizing the amorphous form of Imatinib mesylate as an intermediate for the preparation of pharmaceutical compositions.
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