The invention discloses a propranolol hydrochloride oral disintegrating tablet used for treating post-traumatic stress disorder, and a preparation method thereof. The oral disintegrating tablet is composed of effective amount of propranolol hydrochloride, a disintegrating agent, and other pharmaceutically acceptable auxiliary materials. According to the preparation method, a modern preparation method is adopted. The product quality is stable. The oral disintegrating tablet has the characteristics of good mouthfeel, convenient application, and fast absorption.

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