专利详细信息
专利号 | CN103385862A |
专利标题 | Metoprolol tartrate sustained-release tablet and preparation method thereof |
专利权人 | CHONGQING GUOZHONG MEDICAL CO LTD; |
发明人 | LI CHAOYANG;ZAN QIONG;TAN ZONGHUA;LI DAFU;XING HUI;WU TONGXUAN; |
申请号 | CN20121140450 |
申请日 | 2012/5/8 |
公开日 | 2013/11/13 |
优先权号 | |
IPC | A61K9/30; A61K31/138; A61K31/205; A61K47/38; A61P9/06; A61P9/08; |
专利类型 | |
法律状态查询 | 查看法律状态 |
The invention provides a metoprolol tartrate sustained-release tablet and a preparation method thereof. The tablet is composed of the components of, by weight: 30-50% of metoprolol tartrate, 15-30% of a sustained-release framework material, 0.35-10.0% of a lubricant, 10.0-30.0% of an adhesive, 0.5-5.0% of a film coating premix, and 10.0-30.0% of purified water. Compared with prior art, the tablet and the method provided by the invention have the advantages of simple preparation method, low production cost, suitability for industrialized productions, no greasy and sticky phenomenon during a production process, and smooth release curve. With the tablet, a sudden release phenomenon of a first time period is prevented, and a phenomenon of unqualified release speed at a first time period is also prevented.
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