专利详细信息
| 专利号 |
 |
| 专利标题 | Benzazepine Derivatives Useful as Vasopressin Antagonists |
| 专利权人 | OTSUKA PHARMA CO LTD [JP]; |
| 发明人 | KONDO KAZUMI [JP];MENJO YASUHIRO [JP];TOMOYASU TAKAHIRO [JP];MIYAMURA SHIN [JP];TOMOHIRA YUSO [JP];MATSUDA TAKAKUNI [JP];YAMADA KEIGO [JP];KATO YUSUKE [JP]; |
| 申请号 | US201314034979 |
| 申请日 | 2013/9/24 |
| 公开日 | 2014/1/23 |
| 优先权号 | |
| IPC | C07D223/16; C07D405/12; C07F9/553; |
| 专利类型 | |
| 法律状态查询 | 查看法律状态 |
The present invention provides a benzazepine compound that can maintain for a long period of time the blood level of tolvaptan enabling to provide the desired pharmaceutical effects. The benzazepine compound of the present invention is represented by general formula (1) wherein R1 represents a -CO-(CH2)n-COR2 group (wherein n is an integer of 1 to 4, and R2 is (2-1) a hydroxy group
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