专利详细信息
| 专利号 |
 |
| 专利标题 | SUBSTITUTED CARBAMOYLCYCLOALKYL ACETIC ACID DERIVATIVES AS NEP INHIBITORS |
| 专利权人 | NOVARTIS AG [CH];KARKI RAJESHRI GANESH [US];KAWANAMI TOSHIO [US];KSANDER GARY MICHAEL [US];LIU QIAN [US];MOGI MUNETO [US];SCHIERING NIKOLAUS [CH];SUN ROBERT [US]; |
| 发明人 | KARKI RAJESHRI GANESH [US];KAWANAMI TOSHIO [US];KSANDER GARY MICHAEL [US];LIU QIAN [US];MOGI MUNETO [US];SCHIERING NIKOLAUS [CH];SUN ROBERT [US]; |
| 申请号 | WO2011EP70066 |
| 申请日 | 2011/11/14 |
| 公开日 | 2012/5/24 |
| 优先权号 | |
| IPC | C07C235/36; A61K31/192; A61K31/216; A61K31/341; A61K31/40; A61K31/437; A61K31/4402; A61P9/08; C07C235/40; C07D207/16; C07D213/55; C07D235/00; C07D257/04; C07D307/52; |
| 专利类型 | |
| 法律状态查询 | 查看法律状态 |
The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, B, X, m and n are defined herein. The invention also relates to a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides pharmaceutical composition of compounds of the invention, and a combination of pharmacologically active agents and a compound of the invention.
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