专利详细信息
专利号 | US8609722B2 |
专利标题 | Anesthetic composition for topical administration comprising lidocaine, prilocaine and tetracaine |
专利权人 | |
发明人 | Fita, Fernando Bouffard; |
申请号 | |
申请日 | |
公开日 | 2013/12/17 |
优先权号 | |
IPC | A61K03124000; |
专利类型 | |
法律状态查询 | 查看法律状态 |
Compositions having a mixture of lidocaine prilocaine and tetracaine or their pharmaceutically acceptable salts. A preferred composition includes the following components in the indicated approximate w/w percentages: 1.5% lidocaine base; 1.5% prilocaine base; 4% tetracaine base and water. In some implementations also included may be about 10% methylpynrolidone; 2% dimethyl sulfoxide; 0.08% topical hyaluronidase; 1.5% guar gum; 1% polyoxyethylenesorbitan monolaurate; 0.5 polyoxyethylenesorbitan monooleate and water to 100%. Such compositions exhibits a high concentration on skin a deep anesthetic effect and a significantly more rapid onset of the anesthetic effect than comparable transdermal anesthetics.
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