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专利详细信息
专利号
EP1990046B1
专利标题 Condensation aerosol containing loxapine or prochlorperazine for inhalation
专利权人 Alexza Pharmaceuticals, Inc.;
发明人 Rabinowitz, Joshua D;Zaffaroni, Alejandro C;
申请号
申请日
公开日 2010/3/31
优先权号
IPC A61K00912000;
专利类型
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The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a composition aspect of the present invention the aerosol comprises particles comprising at least 5 percent by weight of an antipsychotic. In a method aspect of the present invention an antipsychotic is delivered to a mammal through an inhalation route. The method comprises a) Heating a composition wherein the composition comprises at least 5 percent by weight of an antipsychotic to form a vapor; and b) allowing the vapor to cool thereby forming a condensation aerosol comprising particles which is inhaled by the mammal. In a kit aspect of the present invention a kit for delivering an antipsychotic through an inhalation route to a mammal is provided which comprises a) a composition comprising at least 5 percent by weight of an antipsychotic; and b) a device that forms an antipsychotic containing aerosol from the composition for inhalation by the mammal.
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