The invention discloses a kind of process for purification of carbidopa comprising: with carbidopa crude product dilute with water transfer below the pH to 6.5 with acid in nitrogen protection or add under the condition of reductive agent and be heated to 50 ℃～110 ℃ obtain the crude product system; In the crude product system add discoloring agent at 50～110 ℃ of decolouring 5～60min; Filtered while hot obtains filtrate after the decolouring and filtrate stirring is cooled to 0～30 ℃ continues to stir 0.5～5h at 0～30 ℃ again obtains refining system; The system of will making with extra care is filtered and filter cake washes the final vacuum drying with water and obtains the carbidopa finished product.The process for purification of carbidopa of the present invention its preparation method is simple controllability is good workable be easy to industrializing implementation and production and its methyldopa removal of impurity is high yield is high the production cost of this process for purification is lower have preferably economic benefit during suitability for industrialized production be easy to apply have broad application prospects.

暂无附图