专利详细信息
专利号 | US20140088310A1 |
专利标题 | Process intermediates and methods for the preparation of process intermediates for the synthesis of argatroban monohydrate |
专利权人 | Lundbeck Pharmaceuticals Italy S.p.a.; |
发明人 | Stivanello, Mariano;Huber, Florian Anton Martin;Ricci, Antonio; |
申请号 | |
申请日 | |
公开日 | 2014/3/27 |
优先权号 | |
IPC | C07D21160000; |
专利类型 | |
法律状态查询 | 查看法律状态 |
Methods are provided for the synthesis of key intermediates for the synthesis of Argatroban monohydrate ethyl (2R4R)-1-[(2S)-2-amino-5-[[imino(nitroamino)methyl]amino]-1-oxopentyl]-4-methylpiperidine-2-carboxylate compounded with HCl. Such intermediates are also provided.
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