专利详细信息
专利号 | CN103536581A |
专利标题 | Nifedipine composition slow releasing capsule |
专利权人 | |
发明人 | |
申请号 | CN20131481596 |
申请日 | 2013/10/15 |
公开日 | 2014/1/29 |
优先权号 | |
IPC | A61K00952000; |
专利类型 | |
法律状态查询 | 查看法律状态 |
The invention provides a kind of Nifedipine composition slow releasing capsule relate to medicine and medicine manufacture technology field by following component made: nifedipine 3.26%~7.27% chitosan nano 63.01%~85.01% magnesium stearate 3.26%~7.27% starch 3.26%~7.27%.Beneficial effect of the present invention is: chitosan nano is the microgranule that a kind of particle diameter is less than 100nm its positively charged can combination with chloride ion because of insoluble absorbability is not drained in external makes Blood pressure drop; Nifedipine and chitosan nano coupling can improve the bioavailability of nifedipine; This compositions can significantly strengthen the effect of the blood pressure lowering of nifedipine can reduce clinically the consumption of nifedipine reduces the untoward reaction of nifedipine.
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