The invention provides a kind of Cyclophosphamide for injection composite freeze-dried powder relate to medicine and medicine manufacture technology field comprise following weight portion material composition: 200～400 parts of cyclophosphamide 100～200 parts of chitosans 4000～8000 parts of waters for injection.Advantage of the present invention is: the invention provides the compositions that a kind of cyclophosphamide mixes by suitable proportion with chitosan nano both have synergism and make injection freeze-dried powder as novel antibacterial medicine for clinical.Advantage of the present invention is: (1) reasonable recipe can increase drug solubility; (2) improve to greatest extent the chemical stability of cryodesiccated cyclophosphamide.(3) collaborative medication the activity of enhancing medicine reduces poisonous side effect of medicine.

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