专利详细信息
专利号 | CN1733764A |
专利标题 | 3-substituted nalidixic acid analog compound and its preparation method and uses in pharmacy |
专利权人 | UNIV CHINA PHARMA [CN]; |
发明人 | LI ZHIYU YOU [CN]; |
申请号 | CN20051041531 |
申请日 | 2005/8/18 |
公开日 | 2006/2/15 |
优先权号 |
CN20051041531 20050818 |
IPC | A61K00314375; A61P003500; C07D022100; C07D047104; |
专利类型 | |
法律状态查询 | 查看法律状态 |
Disclosed is a 3-substituted nalidixic acid analog compound and its preparation method and uses in pharmacy, wherein the compound has antineoplastic activity and a general formula (I) with the 3-position substituted by benzimidazole and benzothiazole, the preparation process of the compound comprises condensing various substituted naphthyridine ketone-3-formylic acid, o-phenylenediamine, o-aminophenol, o-aminobenzenethiol and into polyphosphoric acids. The compound can be used in preparing anti-cancer medicaments.
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