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DESHPANDE PANDURANG BALWANT [IN](10)
LUTHRA PARVEN KUMAR [IN](5)
ORCHID CHEMICALS & PHARM LTD [IN](5)
ALEMBIC LTD [IN](3)
RAMAKRISHNAN ARUL [IN](2)
NILESH BALKRISHNA SHRIGADI [IN](2)
KHADANGALE BHAUSAHEB PANDHARIN [IN](2)
UNICHEM LAB LTD [IN](2)
RAMASUBBU CHANDRASEKARAN [IN](1)
DESHPANDE PRAMOD NARAYAN [IN](1)
专利信息
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公开号
公开日
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申请日
1.
WO2008023383A1
2008/2/28
WO2006IN00432
2006/10/26
专利标题
:NOVEL PROCESS FOR THE PREPARATION OF TELITHROMYCIN
专利权人
:
ALEMBIC LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
PATEL MANISH KANCHANBHAI [IN]
;
KALPESH HARIBHAI DHAMELIYA [IN]
;
LUTHRA PARVEN KUMAR [IN]
;
The present invention relates to the process for the preparation of compounds of formula (I) or its pharmaceutically acceptable salts wherein, (R) is a.
2.
WO2007113845A1
2007/10/11
WO2006IN00172
2006/5/22
专利标题
:A PROCESS FOR THE PREPARATION OF (E)-2-CYANO-3-(3, 4-DIHYDROXY-5-NITROPHENYL)-N, N-DIETHYL-2-PROPENAMIDE (ENTACAPONE)
专利权人
:
ALEMBIC LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
LUTHRA PARVEN KUMAR [IN]
;
PANDEY ANAND KUMAR [IN]
;
DHAMELIYA DHARMESH RAMNIKLAL [IN]
;
The present invention relates to an 'improved process for the preparation of (E)-N, N- diethyl-2-cyano-3- (3, 4-dihydroxy-5-nitrophenyl) acrylamide formula (I) comprising steps of, (a) condensation of 3, 4-dihydroxy-5-nitrobenzaldehyde with N, N-diethylcyanoacetamide in the presence of a catalyst and optionally in the presence of phase transfer catalyst in a solvent selected from the group comprising of ethylacetate, acetonitrile, hydrocarbon such as toluene, xylene and like or mixture thereof t...
3.
WO2007110880A2
2007/10/4
WO2007IN00117
2007/3/21
专利标题
:A PROCESS FOR THE PURIFICATION OF ROPINIROLE HYDROCHLORIDE
专利权人
:
ALEMBIC LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
LUTHRA PARVEN KUMAR [IN]
;
ACHARYA HITARTH HARSHENDU [IN]
;
The present invention provides an improved process for the purification of Ropinirole hydrochloride of formula (Ia) comprising steps of: (i) treating Ropinirole hydrochloride with sodium dithionate and charcoal in suitable alcoholic solvent
4.
WO2006106526A1
2006/10/12
WO2005IN00265
2005/8/9
专利标题
:PROCESS FOR PREPARATION OF CALCIUM SALT OF ROSUVASTATIN
专利权人
:
UNICHEM LAB LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
RAMAKRISHNAN ARUL [IN]
;
NILESH BALKRISHNA SHRIGADI [IN]
;
SANDEEP MUKUNDA BAHUL [IN]
;
The invention relates to commercially viable process for the preparation of Rosuvastatin by an early introduction of correct absolute stereochemistry at C-5 (S) of Rosuvastatin side chain followed by regioselective chain extension using novel side chain building blocks and less expensive reagents. It is yet another object of the invention is to provide novel intermediates that may be used for the preparation of Calcium salt of Rosuvastatin.Formula (I).
5.
WO2006100689A1
2006/9/28
WO2005IN00266
2005/8/9
专利标题
:PROCESS FOR PREPARATION OF ROSUVASTATIN
专利权人
:
UNICHEM LAB LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
RAMAKRISHNAN ARUL [IN]
;
NILESH BALKRISHNA SHRIGADI [IN]
;
RANJIT ANIL GOKHALE [IN]
;
The invention relates to commercially viable process for the preparation of Rosuvastatin by an early introduction of the correct absolute stereochemistry at C-5 (S) of Rosuvastatin side chain followed by regioselective chain extension using novel side chain building blocks. It is yet another object of the invention is to provide novel intermediates that may be used for the preparation of Rosuvastatin. Formula (I).
6.
WO2004111059A1
2004/12/23
WO2004IB01995
2004/6/16
专利标题
:A PROCESS FOR THE PREPARATION OF A CEPHALOSPORIN ANTIBIOTIC
专利权人
:
ORCHID CHEMICALS & PHARM LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
SAHOO PRABHAT KUMAR [IN]
;
VEMPALI ANANDAM [IN]
;
GHANTA SRINIVASU [IN]
;
An improved process for the preparation of ceftriaxone sodium comprising the steps of : i) reacting the 3-cephem derivative of formula (II) with halo acid derivative of formula (III) wherein X represents halogen and Y represent halogen in the presence of silylating agent and methylene chloride at -25 to 10 DEG C, to produce (IV), ii) quenching the reaction by pouring the reaction mixture into water or in a aqueous solution of sodium carbonate, iii) preparing sodium salt solution of (IV) by addi...
7.
WO2004048387A1
2004/6/10
WO2003IB05310
2003/11/19
专利标题
:AN IMPROVED PROCESS FOR THE PREPARATION OF CEFPODOXIME PROXETIL
专利权人
:
ORCHID CHEMICALS & PHARM LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
DAS GAUTAM KUMAR [IN]
;
LUTHRA PARVEN KUMAR [IN]
;
DESHPANDE PRAMOD NARAYAN [IN]
;
SUBRAMANIAN SELVRAJ [IN]
;
KAMMA RAMAKRISHNA [IN]
;
An improved process for the preparation of cefpodoxime proxetil of the formula (I) the said process comprises reacting cefpodoxime acid with 1-haloethyl isopropyl carbonate of the formula (VI) where X represents halogen atom such as chlorine, bromine or iodine using a base such as tetramethylguanidine, di-isopropylethyl amine, 1,5-diazabicyclo(4.3.0)non-5-ene (DBN), 1,4-diazabicyclo[2.2.2]octane (DABCO) in the presence of a solvent at a temperature in the range of -30 DEG C to 30 DEG C to produc...
8.
WO2004046154A1
2004/6/3
WO2003IB05032
2003/11/10
专利标题
:NOVEL AMORPHOUS HYDRATE OF A CEPHALOSPORIN ANTIBIOTIC
专利权人
:
ORCHID CHEMICALS & PHARM LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
KHADANGALE BHAUSAHEB PANDHARIN [IN]
;
RAMASUBBU CHANDRASEKARAN [IN]
;
A process for the preparation of cefdinir of the formula (I) the said process comprising the steps of :i) condensing 7-amino-3-cephem-4-carboxylic acid of the formula (XII) wherein R1 is as defined above with compound of the formula (XIII) in the presence of a tertiary amine and an organic solvent, followed by treatment with a base to produce a salt of compound formula (XIV), wherein M+ is a counter ion and ii) hydrolyzing the compound of the formula (XIV) using an acid in the presence of a solv...
9.
WO2004039812A1
2004/5/13
WO2002IB05459
2002/12/18
专利标题
:PROCESS FOR THE PREPARATION OF 3-PROPENYL CEPHALOSPORIN DMF SOLVATE
专利权人
:
ORCHID CHEMICALS & PHARM LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
KHADANGALE BHAUSAHEB PANDHARIN [IN]
;
GURUSAMY KUMAR [IN]
;
KONDA RAMESH ATHMARAM [IN]
;
The present invention relates to an improved process for the preparation of 3-propenyl cephalosporin DMF solvate, more particularly, the present invention relates to an improved process for the preparation of cefprozil DMF solvate of the formula (I), which is useful for the preparation of cefprozil of the formula (XIV).
10.
WO03099826A1
2003/12/4
WO2002IB01781
2002/5/23
专利标题
:A NEW PROCESS FOR THE PREPARATION OF CEFDITOREN USING THE THIOESTER OF THIAZOLYLACETIC ACID
专利权人
:
ORCHID CHEMICALS & PHARM LTD [IN]
;
DESHPANDE PANDURANG BALWANT [IN]
;
LUTHRA PARVEN KUMAR [IN]
;
The present invention provides a process for the preparation of Cefditoren of formula (I) which comprises acylating 7-amino-cephem carboxylic acids of the general formula (IV), where R3 is hydrogen or trimethylsilyl with thioester derivatives of the formula (II), where R1 represents C1 - C4 alkyl or phenyl in an organic solvent in the presence of an organic base at a temperature in the range of -10 DEG C to 30 DEG C.
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