Sodium ibuprofen compositions and methods of manufacturing tablets and caplets comprising sodium ibuprofen are described. The formulation is advantageous because it allows for the formation of tablets having low sodium content and further provides tablets exhibiting improved physical stability high tablet hardness and high strength coupled with excellent dissolution and bioavailability characteristics. The formulations and processes are further advantageous because they can be produced in large ...

Sodium Ibuprofen Tablets And Methods Of Manufacturing Pharmaceutical Compositions Including Sodium Ibuprofen Abstract The invention broadly relates to sodium ibuprofen compositions and methods of manufacturing tablets and caplets comprising sodium ibuprofen are described. The formulation is advantageous because it allows for the formation of tablets having low sodium content and further provides tablets exhibiting improved physical stability, high tablet hardness and high strength, coupled with ...

A combination of temsirolimus and trastuzumab in the treatment of cancer is provided. A combination of temsirolimus and HKI-272 is provided. A combination of a trastuzumab and a HKI-272 is also provided. Regimens and kits for treatment of metastatic breast cancer containing trastuzumab temsirolimus and/or HKI-272 optionally in combination with other anti-neoplastic agents or immune modulators are described.

Abstract 593502 The disclosure relates to a composition comprising vitamin B1 vitamin B2 niacin vitamin B6 pantothenic acid vitamin E vitamin C and selenium wherein the weight ratio of biotin to vitamin B1 is between 1:20 to 1:25; wherein the weight ratio of biotin to vitamin B2 is between 1 :20 to 1 :25; wherein the weight ratio of biotin to niacin is between 1:310 to 1:330; wherein the weight ratio of biotin to vitamin B6 is between 1:30 to 1:35; wherein the weight ratio of biotin to pantothen...

A combination of HKI-272 compound and a vinorelbine compound in the treatment of a neoplasm is provided. Regimens kits and methods for treatment of neoplasm including breast cancer including metastatic breast cancer and lung cancer using this combination optionally in combination with other anti-neoplastic agents or immune modulators are also described.

Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have the structure: wherein R1 R2 R3 R4 R5 and Q1 are defined herein.

A combination of a 4-anilino-3-cyanoquinoline compound (e.g. HKI-272 SKI-606 EKB-569) and a capecitabine compound in the treatment of a neoplasm is provided. Regimens kits and methods for treatment of neoplasm including breast cancer including metastatic breast cancer and lung cancer using this combination optionally in combination with other anti-neoplastic agents or immune modulators are also described.

The invention relates to 2-methyl-1-(phenylsulfonyl)-4-(piperazin)-1-yl-1H-benzimidazole compounds or a pharmaceutically acceptable salt pharmaceutical composition and use thereof as a medicament and for modulation of 5-HTactivity.