PURPOSE: A pharmaceutical composition containing a beta-blocker is provided to prevent and treat obesity, metabolic diseases including diabetes, caused by obesity, osteopenia, and osteoporosis. CONSTITUTION: A pharmaceutical composition for preventing or treating obesity, metabolic disease caused by obesity, or osteopenia contains 0.001-50 wt% of a beta-blocker as an active ingredient. The beta-blocker is denoted by chemical formula 1. The beta-blocker is non-selective beta-blocker. The beta-blo...

PURPOSE: A composition is provided to include gingerenone A which exhibits the suppression effect of cancer cell proliferation and the expression increasing effect of cleaved-PARP and cleavedcaspase-3 as an active ingredient. CONSTITUTION: A food composition for cancer prevention includes gingerenone A indicated as a chemical formula 1 as an active ingredient. The composition includes 0.000001-50 weight% of the gingerenone based on the whole composition. The food composition for cancer preventio...

PURPOSE: A composition for preventing or treating alopecia caused by anticancer therapy and a method for preventing or treating alopecia are provided to reduce hair follicle dystrophy and the generation of side effects, to promote primary hair recovery, and to maximize therapeutic effects by preventing and/or suppressing alopecia caused by side effects when the composition is used with anticancer therapy. CONSTITUTION: A pharmaceutical composition for preventing or treating alopecia due to chemo...

PURPOSE: A precious metal supported catalyst dipped to even porosity carbon, the manufacturing method thereof, and a method of manufacturing Tetrahydrofuran from succinic acid using the catalyst are provided to have regular pore structure, have excellent physical property having wide specific surface area, and large pore volume, let the precious metal highly diffused inside the even pore of carbon carrier, and have excellent catalyst activity. CONSTITUTION: A precious metal supported catalyst co...

PURPOSE: A manufacturing method of an aloe adventitious root is provided to induce an adventitious root from aloe and to increase the amount of aloe emodin and aloesin culturing in a culture medium. CONSTITUTION: Aloe plant explants are sterilized. The sterilized aloe plant explants are used to induce an adventitious root to dentate in a medium containing plant growth hormone and to be fertilized in a solid medium or a liquid medium. A precursor is treated where the aloe adventitious root is pro...

PURPOSE: A spermine copolymer is provided to remarkably improve transduction effectiveness without cytotoxicity as a hexane-carrier, thereby capable of being used as a hexane-carrier for gene-therapy. CONSTITUTION: A spermine copolymer of which primary amine or secondary amine is combined with at least one acrylate terminal of a linker through an addition reaction is represented by chemical formula 1. A molecular weight of the copolymer is 3-15 kDa. Polyethyleneglycol, galactosylated polyethylen...

The present invention relates to a spermine copolymer and to gene therapy using the spermine copolymer as a nucleic-acid carrier. The spermine copolymer of the present invention is formed by copolymerizing spermine (SPE) using a linker compound that contains two or more hydroxyl groups, and thus may exhibit superior binding capacity in therapeutic nucleic acids such as DNA, effectively protect DNA from nucleases, and exhibit physico-chemical properties appropriate for use as a nucleic-acid carri...

PURPOSE: A pharmaceutical composition containing a conditioned medium prepared by three dimensional culture is provided to regenerate blood vessel in ischemic vascular diseases and to effectively treat ischemic vascular diseases. CONSTITUTION: A pharmaceutical composition for treating ischemic diseases contains conditioned medium as an active ingredient, prepared by three-dimensional culture of adult stem cells using a culture medium. The adult stem cells are adipose-derived stem cells, umbilica...

PURPOSE: A ruthenium catalyst supported on porous carbon support synthesized by a surfactant-templating method, a method for preparing the same, and a method for producing gamma-butyrolactone using the catalyst are provided to activate the hydrogenation of succinic acid. CONSTITUTION: A method for preparing a ruthenium catalyst supported on porous carbon support includes the following: a carbon precursor and a surfactant are dissolved in an acid solution, and a silica precursor is added into the...