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FRESENIUS KABI ONCOLOGY LTD [IN](9)
LAHIRI SASWATA [IN](2)
FRESENIUS KABI ONCOLOGY LTD [IN](1)
MISHRA BHUWAN BHASKAR [IN](1)
PANDA NILENDU [IN](1)
GUPTA NITIN [IN](1)
AZIM ABUL [IN](1)
SANGHANI SUNIL [IN](1)
SHARMA ASWINI KUMAR [IN](1)
GIRI ABHISHEK [IN](1)
专利信息
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公开号
公开日
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申请日
1.
US2014058119A1
2014/2/27
US201213625155
2012/9/24
专利标题
:PROCESS FOR THE PREPARATION CABAZITAXEL
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
The present invention discloses a process for the preparation of 4-acetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1-hydroxy-7beta,10beta-dimethoxy-9-oxotax-11-en-13alpha-yl(2R,3S)-3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionate Cabazitaxel (I).
2.
WO2014020553A1
2014/2/6
WO2013IB56285
2013/7/31
专利标题
:SALTS OF PRALATREXATE
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
The present invention provides salts of Pralatrexate, in particular, sodium, lithium and potassium salts and their polymorphic forms, process for the preparation thereof, pharmaceutical compositions comprising these salts and at least one pharmaceutically acceptable excipient, and the use of pharmaceutical composition for the treatment of conditions related to human tumors.
3.
WO2014016740A2
2014/1/30
WO2013IB55912
2013/7/18
专利标题
:IMPROVED PROCESS FOR THE PREPARATION OF PRALATREXATE
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
An improved process for the preparation of Pralatrexate which is less hazardous. The invention further relates to novel intermediates and process thereof useful for the preparation of Pralatrexate. The present invention also relates to a substantially pure Pralatrexate and a process for obtaining the same in high yield.
4.
WO2013179248A1
2013/12/5
WO2013IB54456
2013/5/30
专利标题
:PHARMACEUTICAL COMPOSITIONS OF PEMETREXED
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
A pharmaceutical composition of Pemetrexed represented by formula (I), which is a liquid ready to use solution formulation or a lyophilized pharmaceutical composition for parenteral administration comprising a pharmaceutically acceptable organic amine, an inert gas and optionally containing at least one or more pharmaceutically acceptable excipients. Also provided are processes for preparation of the ready to use solution formulation or lyophilized pharmaceutical composition of the present inven...
5.
WO2013144814A1
2013/10/3
WO2013IB52356
2013/3/25
专利标题
:STABLE READY-TO-USE PHARMACEUTICAL COMPOSITION OF PEMETREXED
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
A stable ready-to-use pharmaceutical composition comprising pemetrexed or pharmaceutically acceptable salts thereof, wherein the composition is free from antioxidants, amino acids and chelating agents. Also provided is a process for preparing a stable ready-to-use pharmaceutical composition comprising the steps: i) purging inert gas into a parenterally acceptable aqueous solvent until the dissolved oxygen content of the solvent comes to less than 7 mg/L, preferably less than 3 mg/L
6.
WO2013136141A1
2013/9/19
WO2012IB54240
2012/8/22
专利标题
:AN IMPROVED PROCESS FOR THE PREPARATION OF ALPHA FORM OF IMATINIB MESYLATE
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
SHARMA ASWINI KUMAR [IN]
;
GIRI ABHISHEK [IN]
;
BISWAL TAPANJYOTI [IN]
;
SINGH GOVIND [IN]
;
LAHIRI SASWATA [IN]
;
An improved process, which is simple, convenient, economical and industrially viable, for the preparation of stable, free flowing, non-hygroscopic crystalline alpha form of Imatinib mesylate, free from the beta form. The process comprises a) providing a clear solution of imatinib base in organic solvent
7.
WO2013080217A2
2013/6/6
WO2012IN00752
2012/11/19
专利标题
:CRYSTALLINE FORMS OF CARBAZITAXEL AND PROCESS FOR PREPARATION THEREOF
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
The present invention discloses Crystalline Forms of 4-acetoxy-2alpha-benzoyIoxy- 5beta-20-epoxy-1-hydoxy-7beta, 10beta-dimethoxy-9-oxotan-11-en-13alpha-y1(2R,3S)-3-tert- butoxycarbony lamino-2-hydoxy-3-phenylpropionate, i.e Cabazitaxel, methods for its preparation and Pharmaceutical compositions thereof.
8.
WO2013069027A1
2013/5/16
WO2012IN00630
2012/9/21
专利标题
:PROCESSES FOR THE PREPARATION OF CABAZITAXEL INVOLVING C(7) -OH AND C(13) -OH SILYLATION OR JUST C(7) -OH SILYLATION
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
LAHIRI SASWATA [IN]
;
GUPTA NITIN [IN]
;
AZIM ABUL [IN]
;
PANDA NILENDU [IN]
;
MISHRA BHUWAN BHASKAR [IN]
;
SANGHANI SUNIL [IN]
;
Disclosed are processes towards Cabazitaxel (I) starting from 10-Deacetylbaccatin (III) that involve steps of either 7-OH monosilylation (passing through formula V) or 7,13-disilylation (passing through formulae XI, XII). Isopropanol Solvates of Cabazitaxel and processes to make this are also described.
9.
US2013109870A1
2013/5/2
US201213663886
2012/10/30
专利标题
:AMORPHOUS FORM OF CABAZITAXEL AND PROCESS FOR ITS PREPARATION
专利权人
:
FRESENIUS KABI ONCOLOGY LTD [IN]
;
FRESENIUS KABI ONCOLOGY LTD [IN]
;
An Amorphous Form of Cabazitaxel is disclosed. It is preferably characterized by an X-ray powder diffraction (XRD) pattern as depicted in FIG.-1. It is prepared by (a) preparing a solution of Cabazitaxel in a suitable solvent and mixture thereof
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