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ASTRAZENECA UK LTD [GB](15)
SHIONOGI & CO [JP](3)
HORBURY JOHN(2)
TAYLOR NIGEL PHILIP(2)
CRABB JEFFREY NORMAN(1)
CREEKMORE JOSEPH RICHARD [US](1)
KOTHARI SANJEEV HUKMICHAND [US](1)
MUELLER BRADFORD J [US](1)
PENG YINGXU [US](1)
专利信息
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条记录, 当前第1/2页。
公开号
公开日
申请号
申请日
1.
EP2709592A1
2014/3/26
EP20120722820
2012/5/17
专利标题
:PHARMACEUTICAL COMPOSITION OF ROSUVASTATIN CALCIUM
专利权人
:
ASTRAZENECA UK LTD [GB]
;
2.
US2014066447A1
2014/3/6
US201313911151
2013/6/6
专利标题
:IMMEDIATE RELEASE PHARMACEUTICAL FORMULATION OF 4-[3-(4-CYCLOPROPANECARBONYL-PIPERAZINE-1-CARBONYL)-4-FLUORO-BENZYL]-2H-PHTHALAZIN-1-ONE
专利权人
:
ASTRAZENECA UK LTD [GB]
;
The present invention relates to a pharmaceutical formulation comprising the drug 4-[3-(4-cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one in a solid dispersion with a matrix polymer that exhibits low hygroscopicity and high softening temperature, such as copovidone. The invention also relates to a daily pharmaceutical dose of the drug provided by such a formulation. In addition, the invention relates to the use of a matrix polymer that exhibits low hygroscopicity...
3.
HK1092462A1
2013/9/13
HK20060112935
2006/11/24
专利标题
:PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN (E)-7-[4- (4-FLUOROPHENYL) -6-ISOPROPYL-2-[METHYL(METHYLSULFONYL) AMINO]PYRIMIDIN -5- YL] (3R, 5S) -3, 5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATES THEREOF
专利权人
:
ASTRAZENECA UK LTD [GB]
;
SHIONOGI & CO [JP]
;
4.
SI1682536T1
2013/7/31
SI20040032031T
2004/10/22
专利标题
:PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN (E)-7-S4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-SMETHYL(METHYLSULFONYL)AMINOC PYRIMIDIN-5-YLC(3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATES THEREOF
专利权人
:
ASTRAZENECA UK LTD [GB]
;
SHIONOGI & CO [JP]
;
5.
PT1682536E
2013/5/6
PT20040768997T
2004/10/22
专利标题
:PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN (E)-7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-[METHYL(METHYLSULFONYL)AMINO] PYRIMIDIN-5-YL](3R,5S)-3,5-DIHYDROXYHEPT-6-ENOIC ACID AND CRYSTALLINE INTERMEDIATES THEREOF
专利权人
:
ASTRAZENECA UK LTD [GB]
;
SHIONOGI & CO [JP]
;
6.
HK1097260A1
2013/2/1
HK20070102328
2007/3/1
专利标题
:INTERMEDIATES FOR THE PREPARATION OF 2-(6-SUBSTITUTED-1,3-DIOXANE-4-YL) ACETIC ACID DERIVATIVES
专利权人
:
ASTRAZENECA UK LTD [GB]
;
7.
CA2835364A1
2012/11/29
CA20122835364
2012/5/17
专利标题
:PHARMACEUTICAL COMPOSITION OF ROSUVASTATIN CALCIUM
专利权人
:
ASTRAZENECA UK LTD [GB]
;
The invention relates to pharmaceutical compositions containing rosuvastatin calcium of formula (I) and processes for their manufacture.
8.
WO2012160352A1
2012/11/29
WO2012GB51105
2012/5/17
专利标题
:PHARMACEUTICAL COMPOSITION OF ROSUVASTATIN CALCIUM
专利权人
:
ASTRAZENECA UK LTD [GB]
;
CREEKMORE JOSEPH RICHARD [US]
;
KOTHARI SANJEEV HUKMICHAND [US]
;
MUELLER BRADFORD J [US]
;
PENG YINGXU [US]
;
The invention relates to pharmaceutical compositions containing rosuvastatin calcium of formula (I) and processes for their manufacture.
9.
US2011251406A1
2011/10/13
US201113166607
2011/6/22
专利标题
:PROCESS FOR THE PREPARATION OF 2-(6-SUBSTITUTED-1,-3-DIOXANE-4-YL) ACETIC ACID DERIVATIVES
专利权人
:
ASTRAZENECA UK LTD [GB]
;
The invention relates to the preparation of 2-(6-substituted-1,3-dioxane-4-yl)acetic acid derivatives of formula (1), where X stands for a leaving group, and R1, R2, and R3 each independently stand for an alkyl group with 1-3 carbon atoms from 4-hydroxy-6-X-substituted-methyl-tetrahydropyran-2-one compounds, where X is as defined above, with the aid of an acetalization agent, in the presence of an acid catalyst. The invention also relates to the novel compounds of formula (1) as well as salts an...
10.
IL166626A
2011/9/27
IL20050166626
2005/2/1
专利标题
:PROCESS FOR THE MANUFACTURE OF THE CALCIUM SALT OF ROSUVASTATIN AND THE PRODUCT OF SAID PROCESS
专利权人
:
ASTRAZENECA UK LTD [GB]
;
HORBURY JOHN
;
TAYLOR NIGEL PHILIP
;
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