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PURDUE PHARMA LP [US](4)
PURDUE PHARMA LP [US](2)
SPITZLEY CHRISTOF [DE](1)
BROEGMANN BIANCA [DE](1)
MUEHLAU SILKE [DE](1)
KYLE DONALD J [US](1)
TAFESSE LAYKEA [US](1)
专利信息
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1.
US2014057931A1
2014/2/27
US201113825241
2011/9/20
专利标题
:BUPRENORPHINE ANALOGS
专利权人
:
KYLE DONALD J [US]
;
TAFESSE LAYKEA [US]
;
PURDUE PHARMA LP [US]
;
The present invention is directed to Buprenorphine Analog compounds of the Formula (I), Formula (IA) or Formula (IB) shown below, wherein R1, R2, R8, R3a, R 3b, G, X, Z and Y are as defined herein. Compounds of the Invention are useful for treating pain, constipation, and other conditions modulated by activity of opioid and ORL-1 receptors.
2.
US2013197020A1
2013/8/1
US201213663033
2012/10/29
专利标题
:Method of Providing Sustained Analgesia With Buprenorphine
专利权人
:
PURDUE PHARMA LP [US]
;
PURDUE PHARMA LP [US]
;
A method of effectively treating pain in humans is achieved by administering buprenorphine in accordance with first order kinetics over an initial three-day dosing interval, such that a maximum plasma concentration from about 20 pg/ml to about 1052 pg/ml is attained, and thereafter maintaining the administration of buprenorphine for at least an additional two-day dosing interval in accordance with substantially zero order kinetics, such that the patients experience analgesia throughout the at le...
3.
US2013165418A1
2013/6/27
US201213708736
2012/12/7
专利标题
:OPIOID AGONIST/OPIOID ANTAGONIST/ACETAMINOPHEN COMBINATIONS
专利权人
:
PURDUE PHARMA LP [US]
;
PURDUE PHARMA LP [US]
;
The invention is directed in part to oral dosage forms comprising a combination of an opioid agonist, acetaminophen and an orally active opioid antagonist, the opioid antagonist being included in a ratio to the opioid agonist to provide a combination product which is analgesically effective when the combination is administered orally, but which is aversive in a physically dependent subject. Preferably, the amount of opioid antagonist included in the combination product provides at least a mildly...
4.
US2012108621A1
2012/5/3
US201113251172
2011/9/30
专利标题
:PHARMACEUTICAL PREPARATION CONTAINING OXYCODONE AND NALOXONE
专利权人
:
BROEGMANN BIANCA [DE]
;
MUEHLAU SILKE [DE]
;
SPITZLEY CHRISTOF [DE]
;
PURDUE PHARMA LP [US]
;
The invention concerns a storage stable pharmaceutical preparation comprising oxycodone and naloxone for use in pain therapy, with the active compounds being released from the preparation in a sustained, invariant and independent manner.
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