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UNITED THERAPEUTICS CORP [US](19)
UNITED THERAPEUTICS CORP [US](2)
SHARMA VIJAY [US](2)
ROTHBLATT MARTINE [US](1)
AUSTER MARTIN [US](1)
BATRA HITESH [US](1)
TULADHAR SUDERSAN M [US](1)
PENMASTA RAJU [US](1)
WALSH DAVID A [US](1)
专利信息
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条记录, 当前第1/2页。
公开号
公开日
申请号
申请日
1.
EP2711024A1
2014/3/26
EP20130188882
2008/9/5
专利标题
:Buffer solutions having selective bactericidal activity against gram negative bacteria and methods of using same
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
A buffer solution with an effective amount of treprostinil and/or treprostinil sodium for use in the treatment of pulmonary arterial hypertension in a human subject in need thereof is provided. The buffer solution is obtainable by a process comprising diluting a starting solution of treprostinil and/or treprostinil sodium with a buffer comprising glycine and having a pH of greater than 10.
2.
US2014018431A1
2014/1/16
US201314030500
2013/9/18
专利标题
:TREPROSTINIL TREATMENT FOR INTERSTITIAL LUNG DISEASE AND ASTHMA
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
The present invention describes methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of Treprostinil or its derivative, or a pharmaceutic...
3.
EP2681204A1
2014/1/8
EP20120752121
2012/3/1
专利标题
:SYNTHESIS OF INTERMEDIATE FOR TREPROSTINIL PRODUCTION
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
4.
US2013289304A1
2013/10/31
US201313933623
2013/7/2
专利标题
:PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN TM
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
5.
KR20130114277A
2013/10/16
KR20137025328
2012/3/1
专利标题
:SYNTHESIS OF INTERMEDIATE FOR TREPROSTINIL PRODUCTION
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
6.
US2013267734A1
2013/10/10
US201313910583
2013/6/5
专利标题
:PROCESS TO PREPARE TREPROSTINIL, THE ACTIVE INGREDIENT IN REMODULIN TM
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
This present invention relates to an improved process to prepare prostacyclin derivatives. One embodiment provides for an improved process to convert benzindene triol to treprostinil via salts of treprostinil and to purify treprostinil.
7.
KR20130109022A
2013/10/7
KR20127034040
2011/6/2
专利标题
:TREPROSTINIL PRODUCTION
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
8.
US2013261187A1
2013/10/3
US201313906585
2013/5/31
专利标题
:COMPOUNDS AND METHODS FOR DELIVERY OF PROSTACYCLIN ANALOGS
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
This invention pertains generally to prostacyclin analogs and methods for their use in promoting vasodilation, inhibiting platelet aggregation and thrombus formation, stimulating thrombolysis, inhibiting cell proliferation (including vascular remodeling), providing cytoprotection, preventing atherogenesis and inducing angiogenesis. Generally, the compounds and methods of the present invention increase the oral bioavailability and circulating concentrations of treprostinil when administered orall...
9.
US2013184295A1
2013/7/18
US201313738232
2013/1/10
专利标题
:METHOD OF IDENTIFYING THERAPIES FOR PULMONARY HYPERTENSION
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
UNITED THERAPEUTICS CORP [US]
;
The present invention is directed to a method of screening for a therapeutic agent useful for treating pulmonary hypertension comprising: contacting an erythrocyte with a candidate therapeutic agent
10.
US2013096200A1
2013/4/18
US201213709270
2012/12/10
专利标题
:TREPROSTINIL TREATMENT FOR INTERSTITIAL LUNG DISEASE AND ASTHMA
专利权人
:
UNITED THERAPEUTICS CORP [US]
;
UNITED THERAPEUTICS CORP [US]
;
The present invention describes methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for the treatment and/or prevention of interstitial lung disease or asthma, or a condition, such as pulmonary fibrosis, associated with interstitial lung disease or a condition associated with asthma. The invention also relates to kits for treatment and/or prevention of such condition that include an effective amount of Treprostinil or its derivative, or a pharmaceutic...
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