The present invention refers to new classes of polymerisable monomers targeting biotin, a biotin derivative, a biotin analogue or a biotinylated molecule and related structures, as well as molecularly imprinted polymers obtainable by polymerisation of at least one of these monomers and at least one cross-linking monomer in the presence of a suitable template molecule. The obtained polymers may be used for separation of biotin and related small molecules, together with larger biotinylated molecul...

A polymerisable monomer (I) containing a recognition cleft for biotin comprises (i) an isophthalic acid derivative or a pyridine-2,6-dicarboxylic acid derivative and (ii) a vinyl-2-aminopyridine derivative for use as part of a molecularly imprinted polymer where X is C or N