The invention is concerned with a transdermal therapeutic system (TTS) comprising buprenorphine and a method of manufacturing such a TTS. The transdermal therapeutic system is used for the transdermal administration of buprenorphine and analogues thereof. In particular, the invention relates to the use of a transdermal therapeutic system (TTS) for analgesic purposes. The TTS according to the invention comprises a transdermal drug delivery composition comprising buprenorphine and an adhesive comp...

An oral film comprising 7-[4-[4-(23-dichlorophenyl)piperazin-1-yl]butoxy]-34-dihydro-1H- quinolin-2-one base or salts or hydrates thereof.

An oral film comprising 7-[4-[4-(23-dichlorophenyl)piperazin-1-yl]butoxy]-34-dihydro-1H-quinolin-2-one base or salts or hydrates thereof.

An oral film comprising 7-[4-[4-(23-dichlorophenyl)piperazin-1-yl]butoxy]-34-dihydro-1H-quinolin-2-one base or salts or hydrates thereof.

The present invention concerns a process for the manufacture of an adamantanamine of formulawherein R R' and X are as defined in the claims which comprises(i) reacting a compound of formulawith thiourea;(ii) subjecting the resulting compound of formulato an acid treatment and(iii) isolating the resulting adamantanamine or a hydrohalogenide thereof. According to the process of the invention valuable pharmaceuticals are obtainable such as Memantine hydrochloride (RR' = methyl) an uncompetitive NM...

An oral film comprising 7-[4-[4-(23-dichlorophenyl)piperazin-1-yl]butoxy]-34-dihydro-1H- quinolin-2-one base or salts or hydrates thereof.

The invention relates to a closed plastic bottle containing oxaliplatin solution a kit comprising the same and a method for the production thereof. The plastic bottle is made of cycloolefin copolymer for example.