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SANKYO CO [JP](21)
BRISTOL-MYERS SQUIBB COMPANY(19)
SQUIBB BRISTOL MYERS CO [US](18)
REDDY RESEARCH FOUNDATION [IN](17)
SANKYO CO(12)
UNIV TEXAS [US](10)
AEROPHARM TECHNOLOGY INC [US](8)
ROBL JEFFREY A [US](6)
Sankyo Company Limited(6)
Kos Life Sciences, Inc.(5)
专利信息
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条记录, 当前第1/27页。
公开号
公开日
申请号
申请日
1.
NZ598548A
2013/9/27
NZ20070598548
2007/8/13
专利标题
:Heterocyclic compounds suitable for the treatment of diseases related to elevated lipid level
专利权人
:
NOVARTIS AG
;
Abstract - 603255 Disclosed is the compound 2-(3-(cyclopropylmethyl)-2-oxo-imidazolidin-1-yl)-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide or a pharmaceutically acceptable salt thereof. Further disclosed is a pharmaceutical composition comprising a therapeutically effective amount of the compound 2-(3-(cyclopropylmethyl)-2-oxoimidazolidin-1-yl)-4-methyl-N-(pyridin-3-ylmethyl)thiazole-5-carboxamide or a pharmaceutically acceptable salt thereof optionally in combination with a therapeutic...
2.
KR20130047458A
2013/5/8
KR20110112506
2011/10/31
专利标题
:Composition for preventing, improving, or treating a disease controlled by ppar action
专利权人
:
KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
;
PURPOSE: A composition containing Dendrobium moniliforme is provided to prevent relieve or treat PPAR activation regulation-related diseases including obesity metabolic diseases and cardiovascular diseases. CONSTITUTION: A composition for preventing or treating PPAR activation regulation-related diseases contains Dendrobium moniliforme as an active ingredient. A composition for health functional food for preventing or treating PPAR activation regulation-related diseases contains Dendrobium monil...
3.
USRE44186E1
2013/4/30
US13/308658
2011/12/1
专利标题
:Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase iv and method
专利权人
:
BRISTOL-MYERS SQUIBB COMPANY
;
Dipeptidyl peptidase IV (DP 4) inhibiting compounds are provided having the formula where x is 0 or 1 and y is 0 or 1 (provided that x=1 when y=0 and x=0 when y=1); n is 0 or 1; X is H or CN; and wherein R1 R2 R3 and R4 are as described herein. A method is also provided for treating diabetes and related diseases especially Type II diabetes and other diseases as set out herein employing such DP 4 inhibitor *or a combination of such DP 4 inhibitor and one or more of another antidiabetic agent such...
4.
US20130085169A1
2013/4/4
US13/637601
2011/4/1
专利标题
:Methods and compositions comprising ampk activator (metformin/troglitazone) for the treatment of myotonic dystrophy type 1 (dm1)
专利权人
:
Inserm (institut National De La Sante Et De La Recherche Medicale)
;
The present invention relates to methods and compositions for the treatment of Myotonic Dystrophy type 1 (DM1) with an AMPK activator .
5.
KR20130015932A
2013/2/14
KR20110078274
2011/8/5
专利标题
:Pharmaceutical composition for treating alzheimer's disease including low dose thazolidinedione
专利权人
:
Industry-academic Cooperation Foundation, Yonsei University
;
PURPOSE: A pharmaceutical composition containing a thiazolidinedione-based drug for preventing and treating Alzheimer's disease is provided to enhance LRP1 expression and the discharge of beta-amyloid into the blood. CONSTITUTION: A pharmaceutical composition for treating neurological disorders contains a thiazolidinedione-based drug as an active ingredient. The thiazolidinedione-based drug includes rosiglitazone pioglitazone or troglitazone. The pharmaceutical composition enhances the LRP1 expr...
6.
EP2552435A1
2013/2/6
EP20110711590
2011/4/1
专利标题
:Methods and compositions comprising ampk activator (metformin/troglitazone) for the treatment of myotonic dystrophy type 1 (dm1)
专利权人
:
Inserm (institut National De La Sante Et De La Recherche Medicale)
;
7.
AU2012265557A1
2013/1/31
AU20120265557
2012/12/17
专利标题
:Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes
专利权人
:
Metaproteomics, Llc
;
C: \NRPortbl\DCC\DAR\489270_l.DOC-17 12/2012 Disclosed are botanically based compositions and methods useful for the treatment of metabolic syndrome and diabetes type 2. Compositions kits and methods are additionally disclosed for means to augment the activity of identified glucose and insulin regulating drugs. Hexahydrocolupulone _-^-7.1 0.57 Spent Hops : 1.11 Beta-Acids 1 .24 Alpha Acids sw ____ _ -' 1 1.45 -_- I _ _ ii _ Xanthohumol rrImm mm - 1.46 Hexahydroisoalpha acids Ir:".E 2 Tetrahydroi...
8.
NZ595024A
2013/1/25
NZ20100595024
2010/3/4
专利标题
:Benzofuranyl derivatives used as glucokinase inhibitors
专利权人
:
PFIZER INC
;
595024 Disclosed herein is a compound which is NN-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)carbomoyl-4-yloxy)pyrimidine-2-carboxamide a pharmaceutical composition comprising it and a pharmaceutical composition further comprising an anti-obesity agent and an anti-diabetic agent. Wherein said anti-obesity agent is selected from the group consisting of dirlotapide mitratapide implitapide lorcaserin cetilistat PYY3-36 naltrexone oleoyl-estrone obinepitide pramlintide tesofensine leptin liraglut...
9.
CN101677983B
2012/12/26
CN2008817319
2008/4/28
专利标题
:Be used to prevent because the compositions of the illeffects that use ppar-gamma agonist causes
专利权人
:
Sigma-tau Industrie Farmaceutiche Riunite S.p.a.
;
10.
CA2543831C
2012/5/29
CA20042543831
2004/10/27
专利标题
:Process for preparing thiazolidinediones
专利权人
:
SANDOZ AG
;
This invention provides a process for reducing an exocyclic double bond at the 5-position of a thiazolidinedione moiety of a thiazolidinedione precursor comprising the steps of: a) preparing a solution or suspension of the thiazolidinedione precursor in a non-ether solvent medium with a base and b) combining the solution or suspension with a dithionite source. Preferred solvent media include aqueous NN-dimethylformamide. Sodium dithionite is a preferred dithionite source. In particular the appli...
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