专利信息

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专利标题：Methods of converting amorphous drug substance into crystalline form

专利权人：Boston Scientific Scimed, Inc.;

A method for converting an amorphous drug such as everolimus or other macrolide immunosuppressive drug into a crystalline form. The method utilizes a slurry of the drug in organic liquid phase and ages the slurry to achieve the conversion.

专利标题：A kind of containing the composition and method of making the same of everolimus and the pharmaceutical preparation that contains this compositions

专利标题：Combinational use of pegylated recombinant human arginase with chemotherapeutic/target therapeutic drug in cancer treatment

专利权人：Cheng, Ning Man;

The present invention provides a method for treatment of cancer comprising administration of an arginine reducing compound and a chemotherapeutic/target therapeutic drug to a subject in need thereof. In one embodiment the cancer is liver cancer or prostate cancer. In another embodiment the arginine reducing compound is pegylated recombinant human arginase and the chemotherapeutic/target therapeutic drug is oxaliplatin everolimus paclitaxel or sorafenib.

专利标题：A kind of tablet containing everolimus and preparation method thereof

专利标题：Lkb1 as predictive marker of everolimus efficacy in breast cancer

专利权人：Centre Leon Berard;

Method for identifying a breast cancer likely to respond to treatment with everolimus comprising the following steps: Measuring the level of expression of the LKB1 gene in a breast tumour sample previously taken from a breast cancer patient Classifying the breast cancer as likely to respond to treatment with everolimus if the LKB1 gene is under- expressed in said breast tumour sample.

专利标题：Process for making trisubstituted silyloxyethyl triflates

专利权人：SYNTHON BV;

An improved process for making stabilizing and monitoring the compound of general formula (3) in which R1R2R3 are independently a straight or branched alkyl group of 1 to 10 carbon atoms and/or a phenyl group is provided. The compounds of formula (3) are important intermediates in making the pharmaceutically active compound everolimus.

专利标题：PROCESS FOR MAKING EVEROLIMUS

专利权人：SYNTHON BV [NL];

专利标题：Compositions and methods for treating breast cancer

专利权人：Merck Sharp & Dohme Corp.;

The instant invention provides methods of treating breast cancer in a subject suffering there from comprising administering a therapeutically effective amount of an mTor inhibitor an anti-IGF-IR antibody and an aromatase inhibitor. In one embodiment of the methods of the invention the mTOR inhibitor is rapamycin a rapamycin analog selected from ridaforolimus everolimus or temsirolimus or a combination thereof. In another embodiment of the methods of the invention the anti-IGF-1 R antibody is sel...

专利标题：Reference marker for everolimus impurity detection and preparation method thereof

专利标题：Administration of mtor inhibitors

Disclosed are methods for treating a patient with an mTOR inhibitor such as AP23573 sirolimus temsirolimus everolimus etc.

当前查询条件: [药品] 包含 'Everolimus '

	查询范围	在当前结果中查询
!	专利类型	发明实用新型外观设计
!	公开号			CN1234
!	申请号			CN1234
!	专利标题		扩展	PHARMA
!	专利权人		扩展	pfizer
	发明人
!	申请日			yyyymmdd
!	公开日			yyyymmdd
	优先权号
!	摘要		扩展	PHARMA
	IPC			A01B

1. US8669360B2	2014/3/11	US13/242433	2011/9/23
专利标题：Methods of converting amorphous drug substance into crystalline form 专利权人：Boston Scientific Scimed, Inc.; A method for converting an amorphous drug such as everolimus or other macrolide immunosuppressive drug into a crystalline form. The method utilizes a slurry of the drug in organic liquid phase and ages the slurry to achieve the conversion.

2. CN103610646A	2014/3/5	CN20131642757	2013/12/5
专利标题：A kind of containing the composition and method of making the same of everolimus and the pharmaceutical preparation that contains this compositions 专利权人：

3. WO2014001956A3	2014/2/20	WO2013IB54971	2013/6/18
专利标题：Combinational use of pegylated recombinant human arginase with chemotherapeutic/target therapeutic drug in cancer treatment 专利权人：Cheng, Ning Man; The present invention provides a method for treatment of cancer comprising administration of an arginine reducing compound and a chemotherapeutic/target therapeutic drug to a subject in need thereof. In one embodiment the cancer is liver cancer or prostate cancer. In another embodiment the arginine reducing compound is pegylated recombinant human arginase and the chemotherapeutic/target therapeutic drug is oxaliplatin everolimus paclitaxel or sorafenib.

4. CN103585122A	2014/2/19	CN20121292909	2012/8/17
专利标题：A kind of tablet containing everolimus and preparation method thereof 专利权人：

5. WO2014001562A1	2014/1/3	WO2013EP63791	2013/7/1
专利标题：Lkb1 as predictive marker of everolimus efficacy in breast cancer 专利权人：Centre Leon Berard; Method for identifying a breast cancer likely to respond to treatment with everolimus comprising the following steps: Measuring the level of expression of the LKB1 gene in a breast tumour sample previously taken from a breast cancer patient Classifying the breast cancer as likely to respond to treatment with everolimus if the LKB1 gene is under- expressed in said breast tumour sample.

6. EP2670758A1	2013/12/11	EP20110709667	2011/3/8
专利标题：Process for making trisubstituted silyloxyethyl triflates 专利权人：SYNTHON BV; An improved process for making stabilizing and monitoring the compound of general formula (3) in which R1R2R3 are independently a straight or branched alkyl group of 1 to 10 carbon atoms and/or a phenyl group is provided. The compounds of formula (3) are important intermediates in making the pharmaceutically active compound everolimus.

7. EP2670756A1	2013/12/11	EP20110707171	2011/3/8
专利标题：PROCESS FOR MAKING EVEROLIMUS 专利权人：SYNTHON BV [NL];

8. WO2013169611A1	2013/11/14	WO2013US39612	2013/5/6
专利标题：Compositions and methods for treating breast cancer 专利权人：Merck Sharp & Dohme Corp.; The instant invention provides methods of treating breast cancer in a subject suffering there from comprising administering a therapeutically effective amount of an mTor inhibitor an anti-IGF-IR antibody and an aromatase inhibitor. In one embodiment of the methods of the invention the mTOR inhibitor is rapamycin a rapamycin analog selected from ridaforolimus everolimus or temsirolimus or a combination thereof. In another embodiment of the methods of the invention the anti-IGF-1 R antibody is sel...

9. CN103387572A	2013/11/13	CN20131300574	2013/7/17
专利标题：Reference marker for everolimus impurity detection and preparation method thereof 专利权人：Chengdu Yacht Bio-tech Co., Ltd.;

10. EP2662082A1	2013/11/13	EP20130179744	2006/11/14
专利标题：Administration of mtor inhibitors 专利权人：Ariad Pharmaceuticals, Incorporated; Disclosed are methods for treating a patient with an mTOR inhibitor such as AP23573 sirolimus temsirolimus everolimus etc.

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