It is disclosed a pharmaceutical effervescent composition suitable for oral administration and having the form of an effervescent tablet containing a constant combination of 450 mg paracetamol and 35 mg citric orphenadrine suitable for the treatment of painful situations due to arthritic and/or muscle and skeleton troubles. The specific feature of said effervescent composition is that it also has for excipients glycine and Isomalt.

The present invention relates to the delivery of analgesics through an inhalation route. Specifically it relates to aerosols containing acetaminophen orphenadrine or tramadol that are used in inhalation therapy. In a method aspect of the present invention an analgesic is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of acetaminophen orphenadrine or tramadol on a solid support to form a vapor; and b) passing air through the heated vapor to pr...

A method of using inactive isomer compositions as drug-resistance-reversal agents and in prophylactic treatment includes the steps of selecting an antihistaminically-inactive isomer of a preselected antihistamine, and making stereoselective use of the antihistaminically-inactive isomer for a clinical purposes. The making step includes choosing one of the following clinical purposes for which to make stereoselective use of the antihistaminically-inactive isomer: treatment of malaria, prophylaxis ...

A method of using inactive isomer compositions as drug-resistance-reversal agents and in prophylactic treatment includes the steps of selecting an antihistaminically-inactive isomer of a preselected antihistamine and making stereoselective use of the antihistaminically-inactive isomer for a clinical purposes. The making step includes choosing one of the following clinical purposes for which to make stereoselective use of the antihistaminically-inactive isomer: treatment of malaria prophylaxis of...

A method of treating a malarial infection includes using orphenadrine as part of treating the infection. The method may use orphenadrine alone or in combination with another antimalarial drug such as chloroquine or with plural antimalarial drugs. Use of orphenadrine in this way may also be used in a method of providing prophylaxis against a malarial infection and as part of a method of treating a malignancy.

A method of treating a malarial infection includes using orphenadrine as part of treating the infection. The method may use orphenadrine alone or in combination with another antimalarial drug, such as chloroquine, or with plural antimalarial drugs. Use of orphenadrine in this way may also be used in a method of providing prophylaxis against a malarial infection, and as part of a method of treating a malignancy.

Disclosed is a propellant free buccal spray composition for transmucosal administration of a pharmacologically active compound using a polar solvent. The active compound is in an amount of between 0.001 and 60 percent by weight of the total composition and is selected from the group of anti-muscle spasm agents consisting of baclofen, botulinum toxin, carisoprodol, chlorphenesin, chlorzoxazone, cyclobenzaprine, dantrolene, metazalone, methocarbamol, orphenadrine, tizanidine, and mixtures thereof,...

The present invention relates to the delivery of analgesics through an inhalation route. Specifically, it relates to aerosols containing acetaminophen, orphenadrine or tramadol that are used in inhalation therapy. In a method aspect of the present invention, an analgesic is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of acetaminophen, orphenadrine or tramadol, on a solid support to form a vapor

The present invention relates to the delivery of analgesics through an inhalation route. Specifically it relates to aerosols containing acetaminophen orphenadrine or tramadol that are used in inhalation therapy. In a method aspect of the present invention an analgesic is administered to a patient through an inhalation route. The method comprises: a) heating a thin layer of acetaminophen orphenadrine or tramadol on a solid support to form a vapor; and b) passing air through the heated vapor to pr...

A method of treating a malarial infection includes using orphenadrine as part of treating the infection. The method may use orphenadrine alone or in combination with another antimalarial drug, such as chloroquine, or with plural antimalarial drugs. Use of orphenadrine in this way may also be used in a method of providing prophylaxis against a malarial infection, and as part of a method of treating a malignancy.