The present invention relates to a novel process for refining Cefmetazole sodium, comprising the steps of: 1) dissolving Cefmetazole sodium material in water, and extracting after adding a water-immiscible organic solvent(s), followed by separating the organic phase containing impurities, to provide an aqueous phase containing Cefmetazole sodium

The present invention relates to a novel process for refining Cefmetazole sodium comprising the steps of: 1) dissolving Cefmetazole sodium material in water and extracting after adding a water-immiscible organic solvent(s) followed by separating the organic phase containing impurities to provide an aqueous phase containing Cefmetazole sodium; 2) treating by adding an alkoxide of alkali metal or alkaline earth metal into the above aqueous phase followed by filtrating the precipitate to provide an...

PURPOSE: Complex antibioitics for preventing and treating infection due to drug resistant strains containing existing cepha antibiotics and a beta-lactamase inhibitor are provided to reduce resistance rate and to ensure remarkable antibacterial activity. CONSTITUTION: Complex antibiotics for preventing and treating infection due to drug resistant strains contains existing cepha antibiotics which are selected from the group consisting of first generation second generation fourth generation and fi...