An improved stable pharmaceutical composition for controlled release of an active ingredient comprises a betalactam antibiotic such as cephalexin cefaclor or their pharmaceutically acceptable hydrates salts or esters as active ingredient a calcium salt and a mixture of hydrophilic polymers selected from the group consisting of at least one sodium alginate and one xanthan gum and with or without hydroxypropyl methylcellulose said composition optionally containing probenecid. The composition may a...

The present invention relates to auxiliary-free agglomerates of a {beta}-lactam antibiotic wherein the {beta}-lactam antibiotic is selected from the group consisting of penicillin V potassium salt amoxicillin trihydrate or cephalexin monohydrate the average volume based grain size of 100 to 1000 microns exhibits the following distribution of grain size: less than 100 microns: 1 to 30 percent; 100 to 500 microns: 10 to 80 percent; 500 to 1000 microns: 10 to 80 percent; greater than 1000 microns: ...

The invention relates to a process for the preparation of cephalexin with the aid of a penicillin amidase immobilized on a crosslinked hydrophilic copolymer which has binding activity for ligands having nucleophilic groups and is in bead form.

The present invention relates to dispersible tablets of cephalexin and a process for their preparation.

The present invention relates to dispersible tablets of cephalexin and a process for their preparation.