The present invention relates to a solid oral pharmaceutical composition comprising fluconazole tinidazole and clindamycin or a pharmaceutically acceptable salt thereof wherein the content of pharmaceutically acceptable excipients is significantly lower than the content of the active principles the use of said composition for oral administration with therapeutic activity for treating sexually transmitted infections.

PURPOSE: A therapeutic composition for periodontal diseases is provided to enable topical administration to a periodontal lesion and to continuously treat periodontitis. CONSTITUTION: A therapeutic composition for topical administration contains 2-50wt% of antibiotics 2-50wt% of polyacrylic acid polymer 2-50wt% of soluble polymer 0.04-10wt% of antioxidative ingredient and remaining amount of an ointment base. The antibiotics include one or more selected among minocycline tetracycline doxycycline...